Results 71 to 80 of about 112,327 (261)
Effect of the alumina micro-particle sizes on the thermal conductivity and dynamic mechanical property of epoxy resin. [PDF]
PLoS One, 2023 Xu Z +7 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
MATEC Web of Conferences, 2015 This research is focused on the preparation of the PVA/TO/NRL coatings for paperboard by using poly(vinyl alcohol) (PVA) as substance and blending with Tung oil (TO) and/or natural rubber latex (NRL) in order to enhance water resistance and dynamic ...
Jianprasert Apichaya +2 more
doaj +1 more source
Vibration Analysis of Vacancy Defected Graphene Sheets by Monte Carlo Based Finite Element Method
Nanomaterials, 2018 The stochastic distributed placement of vacancy defects has evident effects on graphene mechanical property, which is a crucial and challenged issue in the field of nanomaterial. Different from the molecular dynamic theory and continuum mechanics theory,
Liu Chu +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Dynamic analysis and criterion evaluation on rockburst considering the fractured dissipative energy
Advances in Mechanical Engineering, 2019 As one of the dynamic disasters of deep mining, rockburst significantly affects the safety of underground environment especially at great depth. First, the elastic energy and dissipative energy are deduced to characterize rockburst process separately ...
Qingwen Li +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Numerical simulation on dynamic compression properties of sandstone under axial static preload
Frontiers in MaterialsIn this study, through a series of static mechanical tests and split Hopkinson pressure bar (SHPB) dynamic impact tests, the static and dynamic mechanical parameters of yellow sandstone are determined, and the Holmquist–Johnson–Cook model parameters of ...
Ying Xu +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source