Results 191 to 200 of about 543,871 (306)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Dynamic Mode Decomposition of Fluorescence Loss in Photobleaching Microscopy Data for Model-Free Analysis of Protein Transport and Aggregation in Living Cells. [PDF]

Sensors (Basel), 2022
Wüstner D.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Dynamic Mode Decomposition (DMD) for Low-Latency Real-Time Cardiac MRI. [PDF]

Magn Reson Med
Yagiz E, Tasdelen B, Ozaslan IK, Jovanovic MR, Tian Y, Nayak KS.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Elucidating motion patterns in sperm cell motion with dynamic mode decomposition. [PDF]

J Biol Phys
Šimánek P, Hořenín J, Khalil ISM, Magdanz V, Klingner A, Kovalenko A.   +5 more
europepmc   +1 more source

WiFi Fingerprinting Indoor Localization Based on Dynamic Mode Decomposition Feature Selection with Hidden Markov Model. [PDF]

Sensors (Basel), 2021
Babalola OP, Balyan V.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

CHOICE AND TEMPORAL WELFARE IMPACTS: DYNAMIC GEV DISCRETE CHOICE MODELS [PDF]

Welfare economics is often employed to measure the impact of economic policies or externalities. When demand is characterized by discrete choices, static models of consumer demand are employed for this type of analysis because of the difficulty in ...
Swait, Joffre, van Bueren, Martin, Adamowicz, Wiktor L.   +2 more
core   +1 more source

Oligomerization of PER2 as a dynamic mode of regulation of the mammalian circadian clock. [PDF]

Proc Natl Acad Sci U S A
Sanyal P, Sharma D, Viswan A, Crosby P, Narayanan V, Baumgartner J, Partch CL, Sekhar A.   +7 more
europepmc   +1 more source