Results 241 to 250 of about 29,837,192 (394)

A dynamic model to sustain the spark: How do network coordinators in Dutch healthcare networks maintain network commitment? [PDF]

PLoS One
Roest M, van der Smissen D, Mannak R, Oerlemans L, Weggelaar-Jansen AM.   +4 more
europepmc   +1 more source

The CL5D Hybrid Model: A Dynamic Systems Approach to High-Fidelity CRISPR-Cas9 Off-Target Prediction via Conjugate Balance Analysis

Chakraborty, Mrinmoy
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A general tribo-dynamic model for lubricated clearance joints in spatial multibody systems. [PDF]

Sci Rep
Liu S, Cui Y, Xing M, Gao L, Zhu F.
europepmc   +1 more source

Dynamically consistent finite volume scheme for a bimonomeric simplified model with inflammation processes for Alzheimer's disease

Barajas-Calonge, Juan, Cortes, Mauricio A. Sepulveda, Torres, Nicolas, Villada, Luis Miguel   +3 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Dynamic Model of Serotonin Presynapse and Its Application to Suicide Attempt in Patients with Bipolar Disorder. [PDF]

Int J Mol Sci
Radenković L, Karanović J, Pantović-Stefanović M, Lazić D, Brajušković G, Ivković M, Pešović J, Savić-Pavićević D.   +7 more
europepmc   +1 more source

FCD Cosmological Model: Fractal Cyclic Dynamic Universe with Active Vacuum and Triptych Time

Daniel Andrés Chillemi
openalex   +1 more source

Study on the Multi-products Dynamic Pricing Model under Uncertain Demands*

, 2012
Longying Li, Tiezhu Zhang
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source