Results 71 to 80 of about 1,347,155 (263)

Scenarios of the Polish economy dynamics in 2017-2022 on the Ramsey type model basis

open access: yesRUDN Journal of Economics, 2019
The article contains a methodology of identification of the dynamic Ramsey model for the Polish economy. It includes two different scenarios of the development of the Polish economy for five years (2017-2022) and the comparison of the forecasts made on ...
Valeriya A Chychuryna, Nikolay N Olenev
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Multi Sensor Fusion Framework for Indoor-Outdoor Localization of Limited Resource Mobile Robots

open access: yesSensors, 2013
This paper presents a sensor fusion framework that improves the localization of mobile robots with limited computational resources. It employs an event based Kalman Filter to combine the measurements of a global sensor and an inertial measurement unit ...
Pedro Albertos   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Trajectory Tracking and Disturbance Rejection Performance Analysis of Classical and Advanced Controllers for a SCORBOT Robot

open access: yesRobotics
This work presents the design and assessment of four control schemes for the monitoring and regulation of joint trajectories applied in the dynamic model of a SCORBOT-ER V plus robot, which includes the dynamics of the actuators, and the estimation of ...
John Kern   +4 more
doaj   +1 more source

Development of pipe crawling robots with vibratory drives and investigation of their kinematic parameters

open access: yesTransport, 2002
In the article the classification of pipe crawling robots with vibratory drives is presented, their advantages and imperfections are reviewed. The schemes of the construction of a pipe crawling robot with a vibratory impulse drive and a pipe crawling ...
Vyganta MiÅ¡tinas   +1 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Resonance Conditions of Gearings. Part I: Analytical Calculation of Resonance Frequencies

open access: yesМеханика машин, механизмов и материалов, 2010
Methods of analytical calculation of resonance conditions of the gearings stipulated by two major factors - periodic change of rigidity of teeth on a phase of engagement and an impact teeth input in engagement in connection with inaccuracy of manufacture
N.N. Ishin   +2 more
doaj  

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