Results 81 to 90 of about 2,014,199 (317)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Kinetic-Dynamic Model for Regulatory Rna Processing [PDF]
, 2008 A kinetic-dynamic model was proposed to simulate RNA processing by determining four essential reaction rates, including the rates of transcription, pre-mRNA turnover, pre -mRNA splicing, and mRNA decay.
Singh, Sher; Yang, Hsiu-Yi Ou; Chen, Mei-Ying; Yu, Sung-Liang +1 more
core
A black-box dynamic equivalent model for microgrids using measurement data [PDF]
, 2014 A dynamic equivalent black-box model, based on Prony analysis is presented. The proposed model is suitable for dynamic studies of microgrids, considering changes in the active and reactive powers, bus voltages, currents and frequency. The developed model
Roscoe, Andrew +5 more
core +1 more source
A Dynamic Model of Commutes [PDF]
Environment and Planning A: Economy and Space, 2005 This paper studies the interaction between commuting, job mobility, and housing mobility. Many conventional models assume that the employment location has priority over the residential location and that the latter is adapted to the former. This implies that commutes which start with a job change will often be short lived because of a change in ...
Jan Rouwendal, Arno van der Vlist
openaire +8 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Analysis of dynamic system optimum and externalities with departure time choice [PDF]
, 2006 This paper aims to analyse the dynamic system optimal assignment with departure time choice, which is an important, yet underdeveloped area. The main contribution of this paper is the necessary conditions and the sensitivity analysis for dynamic system
Chow, A.H.F.
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Dynamic Models of Fresh-cut Spinach in Different Cold Storage Temperature
Zhileng xuebao, 2015 The best treatment design of fresh-cut spinach was established by using orthogonal test. Spinaches were firstly immersed in two solutions (75 mg/LClO2 and 0.5% NaCl) for 10 minutes successively, and then packed with PVDC cling film.
Wang Chao +3 more
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Crosstalk and signalling switches in mitogen-activated protein kinase cascades
Frontiers in Physiology, 2012 Mitogen-activated protein kinase (MAPK) cascades control cell fate decisions, such as proliferation, differentiation and apoptosis by integrating and processing intra- and extracellular cues.
Dirk eFey +3 more
doaj +1 more source