Results 111 to 120 of about 5,533,289 (316)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Dynamics of Immunological Models

Acta Biotheoretica, 2010
We analyse the effect of the regulatory T cells (Tregs) in the local control of the immune responses by T cells. We obtain an explicit formula for the level of antigenic stimulation of T cells as a function of the concentration of T cells and the parameters of the model.
Pinto, A. A., Burroughs, N. J., Ferreira, Miguel, Oliveira , B. M. P. M.   +3 more
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Estimation and Control of WRRF Biogas Production

Energies
The development of resource-efficient digital technologies is a critical challenge in the wastewater sector. This industrial case study, conducted in collaboration with the Veas Water Resource Recovery Facility in Norway, focused on creating data pre ...
Tiina M. Komulainen, Kjell Rune Jonassen, Simen Gjelseth Antonsen   +2 more
doaj   +1 more source

Identifiability in dynamic network identification [PDF]

, 2015
Dynamic networks are structured interconnections of dynamical systems driven by external excitation and disturbance signals. We develop the notion of network identifiability, a property of a parameterized model set that ensures that module dynamics are ...
Weerts, HHM Harm, Hof, Van den, P.M.J., Dankers, AG Arne, Hof, Van den, P.M.J.; id_orcid, Hof, PMJ Paul van den, Dankers, A.G., Weerts, H.H.M.   +6 more
core   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Folder 6: Model engine data sheets and operating instructions, J - N, ca. 1960, 1972, 1988

, 1960
Instructions, illustrations, and parts price list for a Dynamic Models, INC. Johnson Engines.
Dynamic Models, Inc.
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Research on Modeling of the Agile Satellite Using a Single Gimbal Magnetically Suspended CMG and the Disturbance Feedforward Compensation for Rotors

Sensors, 2012
The magnetically suspended Control Moment Gyroscope (CMG) has the advantages of long-life, micro-vibration and being non-lubricating, and is the ideal actuator for agile maneuver satellite attitude control. However, the stability of the rotor in magnetic
Ning Yan, Peiling Cui
doaj   +1 more source

Dynamic Modeling and Simulation of a Space-based Manipulator System

, 2016
In this paper, a complete dynamic modeling process for a space-based n-DOF manipulator system is first presented, which is leading to a new method for modeling the general motion equation.
Chen ZC(陈正仓)
core