Results 111 to 120 of about 2,018,771 (302)

Long-Term Functionality of Rural Water Services in Developing Countries: A System Dynamics Approach to Understanding the Dynamic Interaction of Causal Factors

, 2015
Research has shown that sustainability of rural water infrastructure in developing countries is largely affected by the dynamic and systemic interactions of technical, social, financial, institutional, and environmental factors that can lead to premature
Abrams L., Abramson A., Alarcon L. F., Amy N. Javernick-Will, Bagheri A., Baumann E., Bazeley P., Berke P., Bossel H., Carter R., Choguill C., Churchman C. W., Cottam H., Davis J., Delbecq A. L., Ferguson A. E., Ford A., Forrester J., Foster T., Godet M., Gratch H. A., Hallowell M. R., Harvey P., Harvey P., Homer J., Homer J. B., Hopkins O., Hsu C., Jeffrey P. Walters, Jimenez A., Joint Monitoring Program (JMP), Jones S., Julius K., Kleemeier E., Linstone H. A., Lockwood H., Ludwig B., Meadow D., Montgomery M., Monto M., Narayan D., Nyirishima R., Prokopy L., Pruyt E., Richmond B., Saldanha J., Sara J., Scholz R. W., Schweitzer R., Sterman J., Sugden S., Sugden S., UNICEF Sierra Leone, United Nations (UN), Veeman T. S., Vennix J., Weaver E. A., Whittington D., Wolstenholme E.   +58 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Estimation and Control of WRRF Biogas Production

Energies
The development of resource-efficient digital technologies is a critical challenge in the wastewater sector. This industrial case study, conducted in collaboration with the Veas Water Resource Recovery Facility in Norway, focused on creating data pre ...
Tiina M. Komulainen, Kjell Rune Jonassen, Simen Gjelseth Antonsen   +2 more
doaj   +1 more source

Correlation of finite-element structural dynamic analysis with measured free vibration characteristics for a full-scale helicopter fuselage [PDF]

The correlation achieved with each program provides the material for a discussion of modeling techniques developed for general application to finite-element dynamic analyses of helicopter airframes.
Dean, M. W., Kenigsberg, I. J., Malatino, R.   +2 more
core   +1 more source

Dynamic modeling of spacecraft in a collisionless plasma [PDF]

, 1977
A new computational model is described which can simulate the charging of complex geometrical objects in three dimensions. Two sample calculations are presented. In the first problem, the capacitance to infinity of a complex object similar to a satellite
Katz, I., Parks, D. E., Wang, S. S., Wilson, A.   +3 more
core   +1 more source

Modeling of Forest Dynamics

Сибирский лесной журнал, 2015
The concept of describing the process of self-thinning stands is considered from the standpoint of the general theory and methods of modeling the dynamics of biological populations and communities. Heterogeneity is one of the fundamental factors that determine the population dynamics of both the evolutionary time, and at the level of the lifetime of ...
F. S. Berezovskaya, G. P. Karev
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Elasticity of demand and highway scheme benefit evaluation [PDF]

, 2005
DIADEM (Dynamic Integrated Assignment and Demand Modelling) software package has been recently introduced to complement the variable demand modeling process.
Koh, Andrew
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source