Results 91 to 100 of about 5,392,800 (262)

Dynamic Modeling and Simulation of a Space-based Manipulator System

open access: yes, 2016
In this paper, a complete dynamic modeling process for a space-based n-DOF manipulator system is first presented, which is leading to a new method for modeling the general motion equation.
Chen ZC(陈正仓)
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Modeling discrete dynamic topics

open access: yes, 2017
Topic modeling is an important area which aims at indexing and exploring massive data streams. In this paper we introduce a discrete Dynamic Topic Modeling (dDTM) algorithm, which is able to model a dynamic topic that is not necessarily present over all ...
Fabio Crestani   +5 more
core   +1 more source

Application of System-Dynamic Modeling to Improve Distribution Logistics Processes in the Supply Chain

open access: yes, 2020
This article presents an approach of improve logistics processes with the system dynamics modeling of two different processes scenarios. System dynamics is used, not only as a causal loop diagram, but calculated measures of end-user satisfaction ...
Sayabek Ziyadin   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Variation in emotion dynamics over time is associated with future relationship outcomes

open access: yesFrontiers in Human Neuroscience
Romantic relationships are defined by emotion dynamics, or how the emotions of one partner at a single timepoint can affect their own emotions and the emotions of their partner at the next timepoint.
Simran K. Johal, Emilio Ferrer
doaj   +1 more source

A First Step Towards Dynamic Hybrid Traffic Modeling

open access: yes, 2015
in Proceedings of 29th European Conf. on modelling and simulation (ECMS), p. 64-70, 2015. arXiv admin note: text overlap with arXiv:1401.6773International audienceHybrid traffic modeling and simulation provide an important way to represent and evaluate ...
Najia Bouha   +7 more
core   +1 more source

Dynamic Bayesian networks with application in environmental modeling and management: A review

open access: yes, 2023
Dynamic Bayesian networks (DBNs) as an extension of traditional Bayesian networks have recently been paid great concern to environmental modeling to capture dynamic processes and support feedback loops.
Hu, Y   +8 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Improving the Flexibility of Coal-Fired Power Units by Dynamic Cold-End Optimization

open access: yesEnergies
Traditional coal-fired power units are required to improve their operational flexibility to accommodate increasing renewable energy. In this paper, an optimized operation approach of the cold-end system is proposed to improve the flexibility of coal ...
Yanpeng Zhang   +7 more
doaj   +1 more source

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