Results 81 to 90 of about 2,018,771 (302)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Integration of dynamic and static modeling on guided inquiry learning can help students to understand chemical concepts at macroscopic, symbolic and microscopic levels.
Indah Langitasari +2 more
doaj +1 more source
Dynamic Modeling and Simulation of a Rotating Single Link Flexible Robotic Manipulator Subject to Quick Stops [PDF]
Single link robotic manipulators are extensively used in industry and research operations. The main design requirement of such manipulators is to minimize link dynamic deflection and its active end vibrations, and obtain high position accuracy during its
Dupac, Mihai, Noroozi, Siamak
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Modeling of Traceability Information System for Material Flow Control Data. [PDF]
This paper focuses on data modeling for traceability of material/work flow in information layer of manufacturing control system. The model is able to trace all associated data throughout the product manufacturing from order to final product.
Ismail, Md. Yusof +3 more
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
On a Dynamical Model of Glasses [PDF]
We analyze a simple dynamical model of glasses, based on the idea that each particle is trapped in a local potential well, which itself evolves due to hopping of neighbouring particles. The glass transition is signalled by the fact that the equilibrium distribution ceases to be normalisable, and dynamics becomes non-stationary.
Bouchaud, Jean-Philippe +2 more
openaire +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A Novel Dual-Motor Two-Speed Direct Drive Battery Electric Vehicle Drivetrain
Although the demand of battery electric vehicle (BEV) growths fast as the requirement of reducing greenhouse gas emission and the usage of fossil fuels, the limited driving range and unfriendly retail price present barriers to BEV to provide comparable ...
Jiageng Ruan, Qiang Song
doaj +1 more source
Towards a Formal Model of Privacy-Sensitive Dynamic Coalitions
The concept of dynamic coalitions (also virtual organizations) describes the temporary interconnection of autonomous agents, who share information or resources in order to achieve a common goal.
Bab, Sebastian, Sarrouh, Nadim
core +2 more sources

