Results 161 to 170 of about 28,178,522 (404)

Numerical modelling of in-plane behaviour of adobe walls [PDF]

, 2010
Some tests for material characterization of adobe blocks and adobe masonry have been carried out in universities and laboratories around the world. However, the number of tests is quite limited in comparison with those carried out with other structural ...
Blondet, M., Camata, G., Spacone, E., Tarque, N., Varum, H.   +4 more
core   +1 more source

Dynamical Transmission of Coronavirus Model with Analysis and Simulation [PDF]

, 2021
Muhammad Farman, Ali Akg黮, Aqeel Ahmad, Dumitru Bǎleanu, Muhammad Umer Saleem   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Integrating Process Re-Engineering Models in Cement Production to Improve Energy Efficiency

Applied Sciences
The demand for cement has significantly increased, growing by 8% in the year 2022 and by a further 12% in 2023. It is highly anticipated that this trend will continue, and it will result in significant growth by 2030. However, cement production is highly
Moses Charles Siame, Tawanda Zvarivadza, Wiyao Edjeou, Isaac N. Simate, Edward Lusambo   +4 more
doaj   +1 more source

DYNAMIC MODELS OF GENTRIFICATION

Advances in Complex Systems
The phenomenon of gentrification of an urban area is characterized by the displacement of lower-income residents due to rising living costs and an influx of wealthier individuals. This study presents an agent-based model that simulates urban gentrification through the relocation of three income groups — low, middle, and high — driven by living costs ...
GIOVANNI MAURO, NICOLA PEDRESCHI, RENAUD LAMBIOTTE, LUCA PAPPALARDO   +3 more
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Flexible Operation of High-Temperature Heat Pumps Through Sizing and Control of Energy Stored in Integrated Steam Accumulators

Energies
Steam networks are widely used for industrial heat supply. High-temperature heat pumps (HTHPs) are an increasingly attractive low-emission solution to traditional steam generation, which could also improve the operational efficiency and energy demand ...
Andrea Vecchi, Jose Hector Bastida Hernandez, Adriano Sciacovelli   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Dynamic Modelling System of Indonesia's Crude Palm Oil Sustainable Supply Chain Management [PDF]

, 2018
The agricultural sector has an important role in economic activity in Indonesia. It is reflected from its contribution to the Gross Domestic Product (GDP) of approximately 13.46 percent in 2016 and its ability to absorb 31.86 percent of Indonesian ...
Cahyadi, E. R. (Eko), Munandar, J. M. (Jono), Muzayanah, F. N. (Fety)   +2 more
core