Results 51 to 60 of about 3,280,097 (317)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Study of the Effect of Temperature on the Capacitance Characteristics of a Metal-μhemisphere Resonant Gyroscope

open access: yesSensors
Metal-μhemispherical resonant gyros (M-μHRGs) are widely used in highly dynamic navigation systems in extreme environments due to their high accuracy and structural stability.
Xiangxian Yao   +4 more
doaj   +1 more source

Research on Channel Characteristics and Electrode Electrical Performance of Earth Current Field Information Transmission Technology

open access: yesSensors, 2023
Starting from the need for emergency rescue information transmission in tunnel engineering accidents, this article focuses on researching and solving the technical problems of information transmission between rescue personnel and trapped personnel after ...
Jingang He   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Simulation of the interactions between multiple hydraulic fractures and natural fracture network based on Discrete Element Method numerical modeling

open access: yesEnergy Science & Engineering, 2020
Obtaining the most Stimulated Reservoir Volume (SRV) by forming a complex fracture network is the prerequisite for shale gas hydraulic fracturing. In this paper, a coupled DFN–DEM model is presented based on a realistic discrete fracture network from ...
Yumei Li
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Research on the Configuration Optimization of All-Metal Micro Resonant Hemisphere

open access: yesSensors
As the core component of the all-metal micro resonant gyroscope, the structural parameters and form and position errors of the resonator significantly influence its vibration characteristics, and consequently, the accuracy of the gyroscope.
Xibing Gu   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Autonomous Navigation in Dynamic Environments

open access: yes, 2007
The purpose of this book is to address the challenging problem of Autonomous Navigation in Dynamic Environments, and to present new ideas and approaches in this newly emerging technical domain.
Chatila, Raja, Laugier, Christian
core   +1 more source

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