In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
From Brittle to Ultraductile: Precise Ionic PEG with Dynamic Networks and Reconfigurable Crystallites. [PDF]
Xu J, Zhang W, Sue HJ, Xie S.
europepmc +1 more source
Central role for neurally dysregulated IL-17A in dynamic networks of systemic and local inflammation in combat casualties. [PDF]
Zamora R +10 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Robust information transfer calculation reveals dynamic networks during sleep arousal. [PDF]
Hohmuth R +3 more
europepmc +1 more source
CNT-Reinforced Self-Healable Epoxy Dynamic Networks Based on Disulfide Bond Exchange. [PDF]
Caglayan C, Kim G, Yun GJ.
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Hydration-Mediated Multiscale Structural Evolution in Polyurethane Hydrogels: From Water States to Microphase Reconstruction and Dynamic Networks. [PDF]
Zhang L +4 more
europepmc +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Robustness, Generalizability, and Heterogeneity of Dynamic Networks of Psychopathology. [PDF]
Jover Martínez A +4 more
europepmc +1 more source

