Results 111 to 120 of about 1,346,444 (348)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Empirical Likelihood: Improved Inference within Dynamic Panel Data Models [PDF]

open access: yes
This paper proposes and analyses an hybrid of Owen's (1988, 1990, 1991) Empirical Likelihood (EL) and bootstrap, EL-bootstrap, as an alternative to the General Method of Moments (GMM) within dynamic panel data models.
Angelica Gonzalez
core  

Hierarchical Bayesian Estimation of Random Co-efficient Dynamic Panel Data Model

open access: diamond, 2021
Akinlade Yemisi Omolara   +3 more
openalex   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Effect of Bank Leverage on Profitability: Focus on Strengthening the Credit System in the Iranian Banking System [PDF]

open access: yesمطالعات مالی و بانکداری اسلامی, 2018
One of the key indicators in the banking sector is bank leverage. Bank leverage refers to how resources are used in the balance sheet to finance the assets. The quality of banking assets has a significant impact on lending in banks.
Mahshid Shahchera, Mahnaz Valizadeh
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Economic Distance and Regional Economic Growth in Iran [PDF]

open access: yesپژوهشهای اقتصادی, 2015
The economic distance refers to the ease or difficulty for goods, services, labor, capital, information, and ideas to traverse space. This variable affects the regional economic growth through influencing location of firms, knowledge spillover and market
zahra dehghan shabani, Nematollah Akbari
doaj  

HABIT FORMATION AND PRECAUTIONARY SAVING: EVIDENCE FROM THE KOREAN HOUSEHOLD PANEL STUDIES [PDF]

open access: yes
We examined the evidence of precautionary saving and Constantinides (1990) type habit formation model by using the Korean Household Panel Studies, which has six years of time series observations and thousands of cross section observations.
Wooheon Rhee
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Detection of Structural Breaks in Linear Dynamic Panel Data Models [PDF]

open access: yes
This paper develops a break detection procedure for the well-known AR(p) linear panel data model with exogenous or pre-determined regressors. The test allows for a structural break in the slope parameters as well as in the fixed effects.
Elias Tzavalis, Stefan de Wachter
core  

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