Results 121 to 130 of about 1,346,444 (348)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Audit committee effectiveness and real earnings management: Ownership structure as a moderator in emerging market

open access: yesCogent Business & Management
This study examines whether audit committee effectiveness constrains real earnings management (REM) in Egypt and whether ownership structure conditions this relationship. Distinct from prior Egyptian and MENA studies that focus primarily on accrual-based
Eman F. Attia   +3 more
doaj   +1 more source

International Tourism Demand for Turkey: A Dynamic Panel Data Approach [PDF]

open access: yes
Empirical studies on tourism field for Turkey have illustrated little attention in modelling properly the demand function for tourism and identifying the main basis of tourism flows.
Aslan, Alper   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

State dependence in work-related training participation among British employees: A comparison of different random effects probit estimators. [PDF]

open access: yes
This paper compares three different estimation approaches for the random effects dynamic panel data model, under the probit assumption on the distribution of the errors. These three approaches are attributed to Heckman (1981), Wooldridge (2005) and Orme (
Panos, Sousounis
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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