Results 191 to 200 of about 11,616,755 (303)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Adaptive vector oriented control of doubly fed induction generator wind turbines using M5P model tree for robust dynamic performance. [PDF]

Sci Rep
Benyoucef K, Abdelhafidh M, Djamel B, Hasan Mujammal MA, Sofiane K, Nassim Z, Bajaj M, Rubanenko O.   +7 more
europepmc   +1 more source

Effects of JFET Region Design and Gate Oxide Thickness on the Static and Dynamic Performance of 650 V SiC Planar Power MOSFETs. [PDF]

Materials (Basel), 2022
Zhu S, Liu T, Fan J, Maddi HLR, White MH, Agarwal AK.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Steady-State Characteristic Assessment and Dynamic Performance Testing for a Metal-Supported Solid Oxide Fuel Cell Auxiliary Power Unit with Methanol On-Board Reforming. [PDF]

ACS Omega
Ma S, Xue K, Jia R, Ren X, Zhao H, Li Y.
europepmc   +1 more source

Optimization of a p-Coumaric Acid Biosensor System for Versatile Dynamic Performance. [PDF]

ACS Synth Biol, 2021
Jiang T, Li C, Yan Y.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Further Evidence on Hedge Funds Performance. [PDF]

In this analysis we identify dynamic hedge fund strategies quantitatively pursuing a Principal Component Analysis following Fung and Hsieh (1997). We extract five dominant hedge fund strategies each representing similar investment styles and analyse the ...
Madsen, Peter Brink, Christiansen, Claus Bang, Christensen, Michael   +2 more
core  

Static and Dynamic Performance of Long-Span Suspension Bridges with Flexible CFRP Central Buckles. [PDF]

Polymers (Basel)
Wang M, Zhang T, Yang H, Zhu Y, Liu B, Liu Y.   +5 more
europepmc   +1 more source

Evaluating the Dynamic Performance of Interfacial Pressure Sensors at a Simulated Body-Device Interface. [PDF]

Can Prosthet Orthot J, 2021
Hamilton M, Sivasambu H, Behdinan K, Andrysek J.   +3 more
europepmc   +1 more source