Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Study on static and dynamic performance of aircraft maintenance hangar under multiple load combinations. [PDF]
Liu X, Chen Z, Zhu F, Chen H.
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Dynamic performance and scenario-based screening strategy of six COPD questionnaires: a cross-sectional study with prevalence-driven robustness validation. [PDF]
Wang Q, Liu L, Zhang Q, Li H, Ma Q.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Advanced Temperature Design for Dynamic Performance Enhancement of PEMFCs Under High Current Density (HCD). [PDF]
Cai F, Cai S, Tu Z, Chan SH.
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Dynamic performance of quasi-zero-stiffness isolator with displacement-dependent electromagnetic shunt damping. [PDF]
Hao P, Niu J, Zhang W.
europepmc +1 more source
Dynamic Performance Analysis of STEP System in Internet of Vehicles Based on Queuing Theory.
Li H, Wu X, Wang Y.
europepmc +1 more source
Dynamic Performance of Laminated High-Damping and High-Stiffness Composite Structure Composed of Metal Rubber and Silicone Rubber. [PDF]
Zheng X, Ren Z, Shen L, Zhang B, Bai H.
europepmc +1 more source

