Results 91 to 100 of about 10,040 (298)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

RESTLESS BANDIT MARGINAL PRODUCTIVITY INDICES II: MULTIPROJECT CASE AND SCHEDULING A MULTICLASS MAKE-TO-ORDER/-STOCK M/G/1 QUEUE [PDF]

This paper develops a framework based on convex optimization and economic ideas to formulate and solve approximately a rich class of dynamic and stochastic resource allocation problems, fitting in a generic discrete-state multi-project restless bandit ...
José Niño-Mora
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Uma Abordagem de escalonamento heterogêneo preemptivo e não preemptivo para sistemas de tempo real com garantia em multiprocessadores [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Automação e SistemasSistemas de tempo real são sistemas onde o correto funcionamento não depende somente da resposta lógica ...
Starke, Renan Augusto
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Load Balance in Hierarchical Communication Networks Based on Dynamic Priority Scheduling

Nanjing Hangkong Hangtian Daxue Xuebao
Targeting smart airports， modern airport communication networks must simultaneously support deterministic low-latency transmission for safety-critical services and high-throughput data delivery.
QIAN Xiaoyan, XU Rui, HAN Lei, GU Yan, LIU Qingsong, ZHENG Zhaoyu   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Heuristics for the Early/Tardy Scheduling Problem with Release Dates [PDF]

In this paper we consider the single machine earliness/tardiness scheduling problem with di?erent release dates and no unforced idle time. We analyse the performance of several dispatch rules, a greedy procedure and a decision theory local search ...
Rui A. F. S. Alves, Jorge M. S. Valente
core  

Agent-Based Adaptive Dynamic Round Robin (AADRR) Scheduling Algorithm

IEEE Access
Scheduling techniques are essential to increase resource utilization and task execution within modern computing environments. Round Robin Scheduling (RR) ensures a fair distribution of processes needing attention but often leads to inefficiencies in ...
Zafar Iqbal Khan, Muzafar Khan, Syed Nasir Mehmood Shah   +2 more
doaj   +1 more source