Results 101 to 110 of about 10,040 (298)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Beam search algorithms for the early/tardy scheduling problem with release dates [PDF]

In this paper we consider the single machine earliness/tardiness scheduling problem with di?erent release dates and no unforced idle time. We present several heuristic algorithms based on the beam search technique. These algorithms include classical beam
Rui A. F. S. Alves, Jorge M. S. Valente
core  

Fuzzy-based dynamic distributed queue scheduling for packet switched networks

, 2013
Addressing the problem of queue scheduling for the packet-switched system is a vital aspect of congestion control. In this paper, the fuzzy logic based decision method is adopted for queue scheduling in order to enforce some level of control for traffic ...
Bakar, Kamalrulnizam A., Chude-Okonkwo, Uche A.K., Sulong, Ghazali, Olisah, Chollette   +3 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Heuristic procedures for reactive project scheduling. [PDF]

This paper describes new heuristic reactive project scheduling procedures that may be used to repair resource-constrained roject baseline schedules that suer from multiple activity duration disruptions during project execution.The objective is to ...
Van de Vonder, S, Ballestin, F, Herroelen, Willy, Demeulemeester, Erik   +3 more
core  

Dynamic Tasks Scheduling with Multiple Priorities on Heterogeneous Computing Systems

2024 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW)
The efficient utilization of heterogeneous computing systems is crucial for scientists and industrial organizations to execute computationally intensive applications. Task-based programming has emerged as an effective approach for harnessing the processing power of these systems.
Tayeb, Hayfa, Bramas, Bérenger, Faverge, Mathieu, Guermouche, Abdou   +3 more
openaire   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Marginal productivity index policies for dynamic priority allocation in restless bandit models [PDF]

, 2009
Esta tesis estudia tres complejos problemas dinámicos y estocásticos de asignación de recursos: (i) Enrutamiento y control de admisión con información retrasada, (ii) Promoción dinámica de productos y el Problema de la mochila para artículos perecederos,
Jacko, Peter
core