Results 121 to 130 of about 10,040 (298)
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
MARGINAL PRODUCTIVITY INDEX POLICIES FOR SCHEDULING A MULTICLASS DELAY-/LOSS-SENSITIVE QUEUE [PDF]
We address the problem of scheduling a multiclass M/M/1 queue with a finite dedicated buffer for each class. Some classes are delay-sensitive, modeling real-time traffic (e.g.
Jose Niño-Mora
core
To address the efficiency and safety challenges arising from the mixed operation of autonomous and human-driven container trucks during the automation transformation of traditional container terminals, this study designed a simulation-based optimization ...
Weili Wang +3 more
doaj +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Project scheduling under undertainty – survey and research potentials. [PDF]
The vast majority of the research efforts in project scheduling assume complete information about the scheduling problem to be solved and a static deterministic environment within which the pre-computed baseline schedule will be executed. However, in the
Herroelen, Willy, Leus, Roel
core
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Quality of service optimization of multimedia traffic in mobile networks
Mobile communication systems have continued to evolve beyond the currently deployed Third Generation (3G) systems with the main goal of providing higher capacity. Systems beyond 3G are expected to cater for a wide variety of services such as speech, data,
Yerima, Suleiman, Yerima, Suleiman Y.
core
Computer control : task synchronisation in dynamic priority scheduling [PDF]
Due to common resource protection, most real-time tasks have non-preemptive sections. Such sections, called critical sections, rise several problems to real-time scheduling theory. Namely, deadlock avoidance and bounded blocking time.
Lopes, Sérgio F. +1 more
core

