Results 161 to 170 of about 100,788 (264)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Performance in IT systems is critical to ensuring that systems meet user needs and expectations. In heterogeneous computing systems (HCS), which consist of processors with varying capabilities, dynamic adaptation plays a vital role in maintaining high ...
Lotfi BENDIAF +2 more
doaj
Optimal control under safety constraints and disturbances: a multi-step, off-policy adaptive dynamic programming approach. [PDF]
Ye J, Zhao X, Bian Y, Hu M, Dong H.
europepmc +1 more source
GADP-align: A genetic algorithm and dynamic programming-based method for structural alignment of proteins. [PDF]
Mirzaei S, Razmara J, Lotfi S.
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
A New Approach to Electrical Fault Detection in Urban Structures Using Dynamic Programming and Optimized Support Vector Machines. [PDF]
Villarreal R +11 more
europepmc +1 more source
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
Improved dynamic programming method for solving multi-objective and multi-stage decision-making problems. [PDF]
Liang Z, Zhao K, He K, Liu Y.
europepmc +1 more source
A Mode of Intelligent Equipment Monitoring Optimization Based on Dynamic Programming Algorithm.
Zheng Z, Jiang C.
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source

