Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Research on energy-saving adaptive optimization of hybrid electric vehicle based on improved dynamic programming and control rule extraction. [PDF]
Sci RepZhao R, Tang L.
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Operating strategy for load service entities using flexible real-time pricing through stochastic dual dynamic programming. [PDF]
Sci RepChoi W, Im J, Lee J, Chung JH, Lee D.
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Revue Nature et TechnologiePerformance in IT systems is critical to ensuring that systems meet user needs and expectations. In heterogeneous computing systems (HCS), which consist of processors with varying capabilities, dynamic adaptation plays a vital role in maintaining high ...
Lotfi BENDIAF +2 more
doaj
Optimal Sliding Mode Fault-Tolerant Control for Multiple Robotic Manipulators via Critic-Only Dynamic Programming. [PDF]
Sensors (Basel)Zhang X, Yang Z, Liu H, Huang X.
europepmc +1 more source
The impact of product quality in a marketing mix model: a dynamic programming approach
reservedThe fundamental question in strategic management is how companies achieve and maintain their competitive advantage. Achieving a successful marketing strategy depends on striking a delicate balance between the four “P’s”.
FERRARA, MARIANNA
core
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Classified modeling and day-ahead optimal scheduling of multi-type adjustable industrial loads in industrial microgrid using improved approximate dynamic programming. [PDF]
Sci RepSun T +5 more
europepmc +1 more source