Results 111 to 120 of about 18,365,131 (347)

Comparison of Sensitivity and Quantitation between Microbead Dielectrophoresis-Based DNA Detection and Real-Time PCR

open access: yesBiosensors, 2017
In this study, we describe a microbead-based method using dielectrophoresis (DEP) for the fast detection of DNA amplified by polymerase chain reaction (PCR).
Michihiko Nakano   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Broadband Spurious-Free Dynamic Range Expander for Microwave Photonic Links Based on Optical Distortion Control

open access: yesIEEE Photonics Journal, 2019
A wideband spurious-free dynamic range (SFDR) expander that uses optical distortion control technique is proposed in this study for microwave photonic links.
Tianwei Jiang   +4 more
doaj   +1 more source

Towards Robustness in Residue Number Systems

open access: yes, 2016
The problem of robustly reconstructing a large number from its erroneous remainders with respect to several moduli, namely the robust remaindering problem, may occur in many applications including phase unwrapping, frequency detection from several ...
Huo, Haiye, Xia, Xiang-Gen, Xiao, Li
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Large dynamic range microwave photonics mixing system based on parallel DPMZM

open access: yesTongxin xuebao, 2021
To solve the problems of nonlinear distortion and limited dynamic range of microwave photonics mixing system, a large dynamic range microwave photonics mixing system based on parallel dual parallel Mach-Zehnder modulator (DPMZM) was proposed.The parallel
Yongsheng GAO   +3 more
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

An Extended Time-Mode Digital Pixel CMOS Image Sensor for IoT Applications

open access: yesSensors
Time-mode digital pixel sensors have several advantages in Internet-of-Things applications, which require a compact circuit and low-power operation under poorly illuminated environments.
Taehyoung Kim, Gunhee Han
doaj   +1 more source

Learning High Dynamic Range from Outdoor Panoramas

open access: yes, 2017
Outdoor lighting has extremely high dynamic range. This makes the process of capturing outdoor environment maps notoriously challenging since special equipment must be used. In this work, we propose an alternative approach. We first capture lighting with
Lalonde, Jean-François, Zhang, Jinsong
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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