Results 111 to 120 of about 4,508,624 (301)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

RESEARCH OF DIGITAL CAMERA DYNAMIC RANGE ON THE IMAGING PROCESSING BASIS

Приборы и методы измерений, 2017
Digital images provide to determine photometric and colorimetric properties of objects subject to validation all elements of a measuring channel (digital camera, software, display) and solve the problem of their limited dynamic ranges.
M Sutkowski, Ya. N. Saukova
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Effective Dynamic Range in Measurements with Flash Analog-to-Digital Convertor

, 2003
Flash Analog to Digital Convertor (FADC) is frequently used in nuclear and particle physics experiments, often as the major component in big multi-channel systems. The large data volume makes the optimization of operating parameters necessary.
D.Z. Liu, H.B. Li, H.T. Wong, J. Li, J.F. Qiu, Lai, Li, Li, Liu, Morris, Q. Yue, S.T. Lin, V. Singh, W.C. Chang, W.P. Lai, Wang, Wong, Zucker   +17 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

On dynamic range reporting in one dimension

Proceedings of the thirty-seventh annual ACM symposium on Theory of computing, 2005
We consider the problem of maintaining a dynamic set of integers and answering queries of the form: report a point (equivalently, all points) in a given interval. Range searching is a natural and fundamental variant of integer search, and can be solved using predecessor search. However, for a RAM with w-bit words, we show how to perform updates in O(lg
Christian Worm Mortensen, Rasmus Pagh, Mihai Patrascu   +2 more
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Log amplifier instrument measures physiological biopotentials over wide dynamic range [PDF]

, 1970
To record biopotentials with extreme dynamic ranges, biopotential inputs are capacitatively coupled to a miniature, low power, solid-state signal conditioner consisting of a two-stage differential preamplifier that has a low noise figure.
Kado, R. T.
core   +1 more source