Results 101 to 110 of about 5,166,941 (333)

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

A simple microscopic model for the dynamics of adhesive failure

, 2005
We consider a microscopic model for the failure of soft adhesives in tension based on ideas of bond rupture under dynamic loading. Focusing on adhesive failure under loading at constant velocity, we demonstrate that bi-modal curves of stress against ...
Mahadevan, L, Mahadevan, L, Vella, D
core   +1 more source

Mechanics of earthquakes [PDF]

, 1994
An earthquake is a sudden rupture process in the Earth’s crust or mantle caused by tectonic stress. To understand the physics of earthquakes it is important to determine the state of stress before, during, and after an earthquake.
Kanamori, Hiroo
core   +1 more source

Role of Weak Materials in Earthquake Rupture Dynamics [PDF]

Scientific Reports, 2019
AbstractWeak materials in seismic slip zones are important in studies of earthquake mechanics. For instance, the exceptionally large slip during the 2011 Tohoku-Oki earthquake has been attributed to the presence of smectite in the fault zone. However, weak fault rocks cannot accumulate large amounts of elastic strain, which is thought to counter their ...
Tetsuro Hirono, Kenichi Tsuda, Shunya Kaneki   +2 more
openaire   +2 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Experimental and numerical study of AA5086-H111 aluminum plates subjected to impact [PDF]

, 2013
An experimental and numerical study of medium-velocity impact (within the range of 120 m/s) has been conducted on thin AA5086-H111 aluminum square plates. Targets with different thicknesses (between 2.5 and 4 mm), stratifications and aluminum alloys have
Abdulhamid, Hakim, Bouvet, Christophe, Kolopp, Amélie, Rivallant, Samuel   +3 more
core   +3 more sources

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Impacts on foam stabilised composite structures: experimental and numerical study [PDF]

, 2003
A dropweight tester is used to make low velocity tests on specific sandwich type structures. Sandwich are made of glass-epoxy skin and polyurethane foam core.
Barrau, Jean-Jacques, Ferrero, Jean-François, Rivallant, Samuel   +2 more
core   +1 more source

Dynamic Rupture Scenarios in the Brawley Seismic Zone, Salton Trough, Southern California

Journal of Geophysical Research: Solid Earth, 2019
In this paper we investigate the dynamic behavior of a system of interconnected faults in the Brawley Seismic Zone (BSZ) in southern California. The system of faults includes the southern San Andreas Fault (SSAF), the Imperial Fault (IF), and a set of ...
C. Kyriakopoulos, D. Oglesby, T. Rockwell, A. Meltzner, M. Barall, J. Fletcher, Drew Tulanowski   +6 more
semanticscholar   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source