Results 191 to 200 of about 450 (229)

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

open access: yesAdvanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin   +5 more
wiley   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

Secure and intelligent 5G-enabled remote patient monitoring using ANN and Choquet integral fuzzy VIKOR. [PDF]

open access: yesSci Rep
Chinnaperumal S   +7 more
europepmc   +1 more source

Cloud Edge-Assisted Verifiable Dynamic Ciphertext Searchable Encryption Scheme

open access: yesProceedings of the 2025 4th International Conference on Cryptography, Network Security and Communication Technology
Yujiao Yuan, Baocheng Wang, Han Zhang
openaire   +1 more source

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