Results 71 to 80 of about 17,020,446 (238)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Dynamic targeting in an online social medium [PDF]

open access: yes, 2012
Online human interactions take place within a dynamic hi- erarchy, where social in uence is determined by qualities such as status, eloquence, trustworthiness, authority and persuasiveness.
Higham, Desmond J.   +5 more
core   +2 more sources

SOQAS: Distributively Finding High-Quality Answerers in Dynamic Social Networks

open access: yesIEEE Access, 2018
Compared with community-based question answering systems and modern search engines, social network-based question answering systems are more efficient in addressing non-factual questions.
Imad Ali   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Social networks of British-Bangladeshi young women [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy by Akter Sina (also known as Sina Akter) and awarded by Brunel University.This research is about the Social Networks and Social Capital of British-Bangladeshi Young Women in relation to ...
Akter, Sina
core   +4 more sources

Real-time updating of dynamic social networks for COVID-19 vaccination strategies. [PDF]

open access: yesJ Ambient Intell Humaniz Comput, 2023
Cheng S, Pain CC, Guo YK, Arcucci R.
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Diffusing information for mobile social networks under consideration of dynamic influence

open access: yesInternational Journal of Distributed Sensor Networks, 2017
As the developments of new techniques, mobile social networks have been built wildly. To obtain and spread information over mobile social networks efficiently, the influence maximization problem is to find a seed nodes set with limited size such that it ...
Dong Jing, Ting Liu
doaj   +1 more source

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