Results 121 to 130 of about 754,490 (317)

The target projection dynamic [PDF]

This paper studies the target projection dynamic, which is a model of myopic adjustment for population games. We put it into the standard microeconomic framework of utility maximization with control costs.
Voorneveld, Mark, Tsakas, Elias
core  

Biomechanical differences between novice and experienced runners: a systematic review

Frontiers in Sports and Active Living
BackgroundRunning offers substantial physical and psychological health benefits, however, novice runners experience a markedly higher incidence of running-related injuries than experienced runners.
Haisheng Shen, Zisheng Jin, Zihui Ma, Hongying Wang   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Resilience optimization and dynamic stability defense in active distribution networks under extreme disasters: a graph learning and cooperative control approach

Frontiers in Energy Research
IntroductionThe escalating integration of high-penetration renewable energy sources introduces severe dynamic stability challenges-such as low inertia and fast transients-to modern power systems, particularly in the context of Active Distribution ...
Chutao Zheng, Wei Li, Xinsen Yang, Diwei Lin, Hao Bai, Guowei Guo   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Verifying PB3D: a new code for 3D ideal linear peeling-ballooning stability [PDF]

, 2016
Magnetic nuclear fusion devices are a promising candidate for the confinement of thermonuclear plasmas but various instabilities set important limits on their operation.
Sánchez, R., Loarte, A, Weyens, T Toon, García, L., Huijsmans, GTA Guido, Huijsmans, G.T.A., Sánchez, R, García , L, Weyens, T., Loarte, A.   +9 more
core  

Innovation-Adjusted Dynamics of E-Waste in the European Union: Mathematical Modeling, Stability and Panel EKC Turning Points

Mathematics
The rapid growth of Waste Electrical and Electronic Equipment (WEEE) in the European Union highlights the need for a rigorous understanding of its long-term dynamics and the role of innovation in shaping its trajectory.
Cristian Busu, Mihail Busu, Stelian Grasu, Sadok Ben Yahia   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Nash Equilibrium and Robust Stability in Dynamic Games: A Small-Gain Perspective

This paper develops a novel methodology to study robust stability properties of Nash equilibrium points in dynamic games. Small-gain techniques in modern mathematical control theory are used for the first time to derive conditions guaranteeing uniqueness
Jiang, Zhong-Ping, Athanasiou, George, Karafyllis, Iasson   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source