Results 131 to 140 of about 754,490 (317)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Analyses of tunnel stability under dynamic loads [PDF]

open access: yes, 2011
Tunnels as any other structures are affected by different loads and stresses. Generally, the loads on tunnels consist of both static and dynamic loads. These loads must both be considered in the tunnel design process.
Hosseini, Navid   +3 more
core  

Rotor angle stability with high penetrations of wind generation

open access: yes, 2012
This paper explores the relationship between wind generation, particularly the control of reactive power from variable speed wind turbine generators, and the rotor angle stability of the conventional synchronous generators in the system.
O\u27Malley, Mark   +6 more
core   +1 more source

Solution of Time Fractional SIQR Epidemic System and Research with Respect to the Fractional Order

open access: yesFractal and Fractional
This article deals with the global existence and uniqueness of solutions to a fractional-order SIQR epidemic model, alongside its intricate chaotic and complex dynamics as functions of the fractional order.
Pingping Li, Zhen Wang, Gongsheng Li
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Some experimental and theoretical studies in aircraft stability at high angles of attack [PDF]

open access: yes, 1983
A review of techniques for stability and response investigations is presented and the averaging technique of Beecham- Titchener-Simpson is applied to the lateral equations of. motion for two combat aircraft.
Thorne, R.
core  

Dinámica de la frecuencia del Sistema InterconectadDinámica Interconectado Ecuador-Colombia; Dinamic of the frequency of the interconected system Ecuador- Colombia

open access: yesRevista Científica de Ingeniería Energética, 2011
En el presente trabajo se propone un procedimiento para estudiar la dinámica de lafrecuencia del sistema interconectado Ecuador-Colombia, ante la salida de unidadesgeneradoras cuando no se dispone de la información necesaria del sistema el ...
Marcelo Arias Castañeda   +1 more
doaj  

Local Dynamic Stability During the 1-Minute Sit-to-Stand Test: Directional Differences and Associations with Body Composition in Healthy Adult Women

open access: yesBiomechanics
Background: The 1 min sit-to-stand test (1-MSTST) is a widely used functional assessment involving repetitive sit-to-stand transitions. This study examined local dynamic stability during the 1-MSTST across three acceleration directions, compared young ...
Arunee Promsri   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy