Results 61 to 70 of about 2,262,838 (324)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Dinámica de la frecuencia del Sistema Interconectado Ecuador-Colombia
This paper presents a procedure to study the dynamics of the frequency of theinterconnected system Ecuador-Colombia when a generation unit comes out of thesystem, and when one doesn't have the necessary information of the electric Colombiansystem ...
Marcelo Arias ; Antonio Martínez
doaj
The dynamic stability of ultra-high voltage alternating current (UHVAC) transmission system with large-scale power bases has not been clearly discussed before.
Qin Jiang, Baohong Li, Tianqi Liu
doaj +1 more source
Dynamics and stability of the Gödel universe [PDF]
We use covariant techniques to describe the properties of the Godel universe and then consider its linear response to a variety of perturbations. Against matter aggregations, we find that the stability of the Godel model depends primarily upon the presence of gradients in the centrifugal energy, and secondarily on the equation of state of the fluid ...
Barrow, John D., Tsagas, Christos G.
openaire +3 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
DYNAMIC MATRIX GAMES AND THEIR MIXED EXTENSION
A new class of game models, called dynamic matrix games (DMG) was introduced in [2] as a generalization of the classical matrix games considering the time factor.
N. N. Danilov
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Temperature dependence of phase stabilities of hexagonal hemicarbides from first principles
Transition metal hemicarbides, specifically M _2 C (where M = V, Nb, Ta, Mo and W), have received considerable attention in the fields of catalysis and metallurgy.
Chao Deng +4 more
doaj +1 more source
For long-distance AC transmission system from energy base to load center, the system damping is insufficient when N–1 fault occurs, which leads to the reduction of transmission capacity.
Guanhong WANG +6 more
doaj +1 more source

