Results 81 to 90 of about 2,353,106 (295)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
We study a dynamic vNM stable set in a compact metric space under the assumption of complete and continuous dominance relation. Internal and external stability are defined with respect to farsighted dominance.
Hannu Vartiainen
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Damage spreading and dynamic stability of kinetic Ising models
, 1996 We investigate how the time evolution of different kinetic Ising models depends on the initial conditions of the dynamics. To this end we consider the simultaneous evolution of two identical systems subjected to the same thermal noise. We derive a master
Coniglio A +11 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Frontiers in Bioengineering and BiotechnologyObjectiveTo investigate the neuromuscular activity characteristics of Tai Chi athletes and identify optimal muscle synergy patterns.MethodData were collected from 12 elite Tai Chi athletes using a Vicon motion capture system, a Kistler 3D force plate ...
Xiaopei Zhang +4 more
doaj +1 more source
Internal stability of reinforced retaining wall under earthquake loads
Yantu gongcheng xuebao, 2018 To analyze the internal stability of reinforced retaining wall under earthquake loads, according to the characteristics of layered filling, stratified compaction and horizontal layered arrangement of reinforcement strip, by selecting the logarithmic ...
JIA Liang 1, HE Shi-kai 1, LI Gang 2, GUO Jian 1, LIANG Rong 1
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source