Results 61 to 70 of about 2,353,106 (295)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
On Dynamical Stability in General Dynamical Systems
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Dinámica de la frecuencia del Sistema Interconectado Ecuador-Colombia
This paper presents a procedure to study the dynamics of the frequency of theinterconnected system Ecuador-Colombia when a generation unit comes out of thesystem, and when one doesn't have the necessary information of the electric Colombiansystem ...
Marcelo Arias ; Antonio Martínez
doaj
The dynamic stability of ultra-high voltage alternating current (UHVAC) transmission system with large-scale power bases has not been clearly discussed before.
Qin Jiang, Baohong Li, Tianqi Liu
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
DYNAMIC MATRIX GAMES AND THEIR MIXED EXTENSION
A new class of game models, called dynamic matrix games (DMG) was introduced in [2] as a generalization of the classical matrix games considering the time factor.
N. N. Danilov
doaj
Electrochemical and Mechanical Properties of Asphalt Concrete Modified by Carbon Microfibers
Carbon microfibers (CMFs) due to their flexibility, durability, conductivity and superior strength have great potential as reinforcement materials in asphalt concrete.
Lijie Ma, Chunfeng Yang, Jishu Sun
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

