Results 161 to 170 of about 8,670 (264)

A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin

open access: yesChemistry – A European Journal, EarlyView.
The first high‐resolution structure of an OGRE‐derived G‐quadruplex from the chicken β‐globin replication origin reveals an intramolecular three‐layer (3+1) hybrid fold with a cytosine bulge and an unprecedented 5'‐outer‐quartet anti guanine, creating a distinctive surface for molecular recognition.
Yingying You   +13 more
wiley   +1 more source

DNA translocation by the CMG helicase: the helical inchworm model. [PDF]

open access: yesBiochem Soc Trans
Batra S   +4 more
europepmc   +1 more source

“Efforts to Surface the Unspoken”: A Mixed Methods Study of a Risk‐Informed Check‐In in Norwegian Family Mediation

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT In family mediation, emotional discomfort and perceived unsafety may signal deeper relational risks, including postseparation violence. Standard intake procedures in Norwegian family mediation depend on disclosure to a nonclinical administrator before any therapeutic relationship exists, and research documents systematic under‐reporting at ...
Jan Stokkebekk   +2 more
wiley   +1 more source

Thresholds: The metaphorical foundations of powerful knowledge

open access: yesThe Curriculum Journal, EarlyView.
Abstract This paper advances a theoretical account of threshold concepts as metaphorical‐relational structures that reorganise meaning across contexts. Building on conceptual metaphor theory, we propose that threshold concepts can be understood as sites of schema‐level reorganisation: deep, embodied patterns of relational logic that scaffold abstract ...
Maria Karrol   +1 more
wiley   +1 more source

New Model of Disuse-Induced Bone Density Loss in Horses. [PDF]

open access: yesAnimals (Basel)
Micheau L   +3 more
europepmc   +1 more source

Strengthening urban resilience in China through underground infrastructures management: Addressing global climate challenges with technological solutions

open access: yesDeep Underground Science and Engineering, EarlyView.
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh   +12 more
wiley   +1 more source

Troubleshooting intrathecal pumps in pain management: A clinical review. [PDF]

open access: yesInterv Pain Med
Wojnowski N   +5 more
europepmc   +1 more source

Developing Transdiagnostic Single‐Session Interventions for University Students Experiencing Disordered Eating: A Mixed‐Method Co‐Design Study

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Many university students encounter barriers to timely support for disordered eating. Brief, scalable digital single‐session interventions (SSIs) may provide an engaging and accessible transdiagnostic pathway for early intervention where there is increased distress before a diagnosis emerges.
Maya Jabs, Tracey D. Wade
wiley   +1 more source

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