Results 101 to 110 of about 3,143,598 (238)
Advanced Science, EarlyView.Chemoresistance is often linked to elevated DNA repair. MPP8 is found to promote breast cancer chemoresistance as a novel NHEJ accessory factor independent of its epigenetic functions. Through multiple protein interactions, MPP8 facilitates association of DNAPK and ligase complexes to promote DNA repair progression.
Rupa Kumari, Jia Fang
wiley +1 more source
Book Review by L. Carr and M. Chandrasekhara of Visualizing dynamic-stall airflows [PDF]
, 1993 This work was done by L. Carr of Ames Research Center and M. Chandrasekhara of the Naval Postgraduate School. Further information may be found in AIAA paper 89A-25511, "Design and Development of a Compression Dynamic Stall Facility".A new wind-tunnel ...
Chandrasekhara, M., Carr, L.
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ActuatorsThe influencing characteristic for the evolution mechanism of a dynamic stall vortex structure and distributed blowing control on rotor airfoils was investigated. Based on the moving-embedded grid method, the finite volume scheme, and Roe’s FDS scheme, a
Guoqiang Li +3 more
doaj +1 more source
Advanced Science, EarlyView.A lactate‐H3K18la epigenetic axis upregulates RPL11 to drive gemcitabine resistance in pancreatic cancer. RPL11 orchestrates chemoresistance through a dual, compartmentalized role: enhancing cytoplasmic protein synthesis via EEF1A1 stabilization and promoting nuclear DNA damage repair by co‐activating PARP14, thus ensuring robust cell survival ...
Lijun Zhao +10 more
wiley +1 more source
Dynamic Stall Control on the Wind Turbine Airfoil via a Co-Flow Jet
Energies, 2016 Dynamic stall control of a S809 airfoil is numerically investigated by implementing a co-flow jet (CFJ). The numerical methods of the solver are validated by comparing results with the baseline experiment as well as a NACA 6415-based CFJ experiment ...
He-Yong Xu +2 more
doaj +1 more source
Habitat‐Specific Design Strategies for Untethered Soft Robots
Advanced Science, EarlyView.Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li +3 more
wiley +1 more source
Analysis of Dynamic Stall on a Pitching Airfoil with Spectral Proper Orthogonal Decomposition [PDF]
, 2022 The onset of dynamic stall on helicopters pitching blades produces massive excursions in the aerodynamic loads that may couple with structure dynamics and cause its earlier failure.
Avanzi, Filippo
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Chinese Journal of Mechanical Engineering, 2019 The unstable flow phenomena in compressors, such as stall and surge, are closely related to the efficiency and the operating region. It is indispensable to capture the unstable flow structure in compressors and understand the mechanism of flow ...
Xiang Xue, Tong Wang
doaj +1 more source
Advanced Science, EarlyView.Oxaliplatin‐resistant colorectal cancer cells utilize a previously unappreciated PLK1‐CEP55‐ESCRT‐driven vesicular extrusion mechanism to clear L‐OHP‐induced cellular damage. The natural withanolide Tubocapsenolide A directly targets and inhibits PLK1 to disrupt this specific damage‐clearance machinery. This blockade induces severe nucleolar stress and
Yueying Yang +15 more
wiley +1 more source
μ-PIV and ELDV wind tunnel investigations of the laminar separation bubble above a helicopter blade tip [PDF]
, 2005 Detailed studies of the boundary layer profile and the characteristics of the flow velocity distribution close to the leading edge of a helicopter blade profile were conducted using the embedded laser doppler velocimetry (ELDV) and stereo-PIV.
Geissler, Wolfgang +6 more
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