Results 51 to 60 of about 2,947,979 (285)

The Dynamics of Static Stall [PDF]

open access: yes, 2011
The dynamic process of flow separation on a stationary airfoil in a uniform flow was investigated experimentally by means of time-resolved measurements of the velocity field and the airfoil's surface pressure distribution. The unsteady movement of the separation point, the growth of the separated region, and surface pressure fluctuations were examined ...
Mulleners, Karen   +3 more
openaire   +3 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Large eddy simulation of dynamic stall over an airfoil and its control with plasma actuator

open access: yesAIP Advances, 2023
The purpose of this study is to investigate deep dynamic stall over a pitching National Advisory Committee for Aeronautics 0015 airfoil and its control with an alternating current dielectric barrier discharge (AC-DBD) plasma actuator by means of large ...
Hengyang Zhang   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Numerical Investigation of a Dynamic Stall on a Single Rotating Blade

open access: yesAerospace, 2021
Dynamic stall is a phenomenon on the retreating blade of a helicopter which can lead to excessive control loads. In order to understand dynamic stall and fill the gap between the investigations on pitching wings and full helicopter rotor blades, a ...
Yin Ruan, Manfred Hajek
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Dynamic Stall Mechanisms of Pitching Airfoil: IDDES Study Across Different Mach Numbers

open access: yesApplied Sciences
This study investigates dynamic stall mechanisms of a pitching NACA 0012 airfoil through high-fidelity computational fluid dynamics (CFD) simulations.
Simeng Jing   +4 more
doaj   +1 more source

Near Stall Unsteady Flow Responses to Morphing Flap Deflections

open access: yesFluids, 2021
The unsteady flow characteristics and responses of an NACA 0012 airfoil fitted with a bio-inspired morphing trailing edge flap (TEF) at near-stall angles of attack (AoA) undergoing downward deflections are investigated at a Reynolds number of 0.62 × 106 ...
Chawki Abdessemed   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Dynamic Stall Characteristics of Thick Wind Turbine Airfoils

open access: yesWind Energy
This paper studies the dynamic stall characteristics of thick flatback and nonflatback wind turbine airfoils. Two airfoils with a maximum thickness of 35% were studied, with trailing edge thicknesses of 2% and 10%, respectively.
Mehdi Doosttalab   +4 more
doaj   +1 more source

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