Results 41 to 50 of about 2,960,271 (286)

The dynamics and timescales of static stall

Journal of Fluids and Structures, 2021
Airfoil stall plays a central role in the design of safe and efficient lifting surfaces. We typically distinguish between static and dynamic stall based on the unsteady rate of change of an airfoil's angle of attack. Despite the somewhat misleading denotation, the force and flow development of an airfoil undergoing static stall are highly unsteady and ...
Sébastien Le Fouest, Julien Deparday, Karen Mulleners   +2 more
openaire   +2 more sources

The Dynamics of Static Stall [PDF]

, 2011
The dynamic process of flow separation on a stationary airfoil in a uniform flow was investigated experimentally by means of time-resolved measurements of the velocity field and the airfoil's surface pressure distribution. The unsteady movement of the separation point, the growth of the separated region, and surface pressure fluctuations were examined ...
Mulleners, Karen, Le Pape, Arnaud, Heine, Benjamin, Raffel, Markus   +3 more
openaire   +3 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Large eddy simulation of dynamic stall over an airfoil and its control with plasma actuator

AIP Advances, 2023
The purpose of this study is to investigate deep dynamic stall over a pitching National Advisory Committee for Aeronautics 0015 airfoil and its control with an alternating current dielectric barrier discharge (AC-DBD) plasma actuator by means of large ...
Hengyang Zhang, Haocheng Yu, Ao Zhang, Jianguo Zheng   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Numerical Investigation of a Dynamic Stall on a Single Rotating Blade

Aerospace, 2021
Dynamic stall is a phenomenon on the retreating blade of a helicopter which can lead to excessive control loads. In order to understand dynamic stall and fill the gap between the investigations on pitching wings and full helicopter rotor blades, a ...
Yin Ruan, Manfred Hajek
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Dynamic Stall Mechanisms of Pitching Airfoil: IDDES Study Across Different Mach Numbers

Applied Sciences
This study investigates dynamic stall mechanisms of a pitching NACA 0012 airfoil through high-fidelity computational fluid dynamics (CFD) simulations.
Simeng Jing, Fan Lu, Li Ma, Qijun Zhao, Guoqing Zhao   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Dynamic Stall Characteristics of Thick Wind Turbine Airfoils

Wind Energy
This paper studies the dynamic stall characteristics of thick flatback and nonflatback wind turbine airfoils. Two airfoils with a maximum thickness of 35% were studied, with trailing edge thicknesses of 2% and 10%, respectively.
Mehdi Doosttalab, Carlos Simao Ferreira, Daniele Ragni, Wei Yu, Christof Rautmann   +4 more
doaj   +1 more source