Results 31 to 40 of about 5,179,304 (300)

Dynamic Stiffness Effect of Mechanical Components on Gear Mesh Misalignment

open access: yesApplied Sciences, 2018
In this work, we propose a method that considers the dynamic elastic stiffness of mechanical components in a quasi-static condition, and we investigate this parameter’s effect on gear mesh misalignment.
Jin-Gyun Kim   +4 more
doaj   +1 more source

Seismic Resistance of Non-Linearly Deformable Large-Span Spatial Structures of Unique Buildings

open access: yesЖелезобетонные конструкции, 2023
Analytical, computer and experimental modeling methods are applied in the study of seismic resistance and changing dynamic parameters of long-term loaded non-linearly deformed large-span spatial shell structures.
Saidmaksud R. Razzakov
doaj   +1 more source

Reliable Dynamic Motions for a Stiff Quadruped [PDF]

open access: yes, 2009
We present a kinodynamic planning methodology for a high-impedance quadruped robot to negotiate a wide variety of terrain types with high reliability. We achieve motion types ranging from dynamic, double-support lunges for efficient locomotion over extreme obstacles to careful, deliberate foothold and body pose selections which allow for precise ...
Roy, Nicholas   +4 more
openaire   +3 more sources

Research on Nonlinear Dynamics Modeling and Simulation of Harmonic Gear Drive

open access: yesJixie chuandong, 2021
Due to the particularity of the structure,the hysteretic stiffness and dynamic friction belong to the inherent properties of harmonic gear drive. Traditional models consider the stiffness as a fixed stiffness or segmented stiffness model,and the friction
Yang Luo   +4 more
doaj  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Dynamically variable negative stiffness structures

open access: yesScience Advances, 2016
A novel active structure supports loads while dynamically and continuously changing stiffness by more than 100× in less than 10 ms.
Christopher B. Churchill   +4 more
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

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