Results 41 to 50 of about 408,399 (309)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Mechanics & Industry, 2023 The development of accurate dynamic stiffness models is a key aspect in the design process of ball screws. However, variations in the nut center of mass position can affect the dynamic stiffness, which makes it difficult to develop a stiffness model.
Jin Lan +3 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Dynamic axial contact stiffness analysis of position preloaded ball screw mechanism
Advances in Mechanical Engineering, 2019 This article establishes an axial contact stiffness model of position preloaded ball screw mechanism based on Hertz contact theory. The analysis of dynamic axial contact stiffness is one of the foundations of the research on the dynamic characteristic of
Jun Liu, Yi Ou
doaj +1 more source
A finite element model using a unified formulation for the analysis of viscoelastic sandwich laminates [PDF]
, 2013 In this paper we present a layerwise finite element model for the analysis of sandwich laminated plates with a viscoelastic core and laminated anisotropic face layers.
Araùjo, A.L. +6 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Out of equilibrium anomalous elastic response of a water nano-meniscus
, 2015 We report the observation of a transition in the dynamical properties of water nano-menicus which dramatically change when probed at different time scales.
Carpentier, Simon +5 more
core +3 more sources
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Research on Nonlinear Dynamics Modeling and Simulation of Harmonic Gear Drive
Jixie chuandong, 2021 Due to the particularity of the structure，the hysteretic stiffness and dynamic friction belong to the inherent properties of harmonic gear drive. Traditional models consider the stiffness as a fixed stiffness or segmented stiffness model，and the friction
Yang Luo +4 more
doaj
Dynamic tooth loads and stressing for high contact ratio spur gears [PDF]
, 1983 An analysis and computer program were developed for calculating the dynamic gear tooth loading and root stressing for high contact ratio gearing (HCRG) as well as LCRG.
Cornell, R. W., Westervelt, W. W.
core +1 more source