Results 41 to 50 of about 149,089 (310)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stiffness in human joints [PDF]

, 1993
Articular stiffness is an important symptom in most arthritic diseases and appears to be a useful marker of disease activity in rheumatoid arthritis.
Helliwell, Philip Stephen
core  

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Research on the dynamic variation law of the discontinuous characteristics of the curvic coupling of aero-engine rotors under working conditions

Engineering Science and Technology, an International Journal
For the design of advanced aero-engine rotor systems under ultra-high rotational speeds, this paper undertakes a comprehensive investigation into the contact stiffness of curvic couplings, which are the key connection mechanism of modern aero-engine ...
Xing Heng, Ailun Wang, Haibiao Zhang, Yijun Yin   +3 more
doaj   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Feedback linearization and simultaneous stiffness-position control of robots with antagonistic actuated joints.

, 2007
In this paper, the dynamic model of a robot with antagonistic actuated joints is presented, and the problem of full linearization via static state feedback is analyzed. The use of transmission elements with nonlinear relation between the displacement and
Hirzinger, Gerd, C. Melchiorri, M. Grebenstein, T. Wimbock, Palli, G., Grebenstein, Markus, MELCHIORRI, CLAUDIO, T. Wimboeck, Melchiorri, C., Wimböck, Thomas, G. Hirzinger, G. Palli, PALLI, GIANLUCA   +12 more
core   +1 more source

Evaluation of dynamic behavior of varved clays from the Warsaw ice-dammed lake, Poland

Open Geosciences, 2023
Soil stiffness degradation due to dynamic loading may result in damage to engineering structures. Therefore, dynamic soil properties gained importance in recent years in the areas where vibrations of different origins are transmitted to the ground.
Nielepkowicz Krzysztof, Dobak Paweł, Bąkowska Anna   +2 more
doaj   +1 more source

A dynamic stiffness model for high-speed ball screw pair with the mass center of screw nut considered

Mechanics & Industry, 2023
The development of accurate dynamic stiffness models is a key aspect in the design process of ball screws. However, variations in the nut center of mass position can affect the dynamic stiffness, which makes it difficult to develop a stiffness model.
Jin Lan, Li Chunhui, Wang Xiao, Xie Liming   +3 more
doaj   +1 more source

Twist and Writhe Dynamics of Stiff Polymers [PDF]

Physical Review Letters, 2000
I consider the dynamics of a stiff filament, in particular the coupling of twist and bend via writhe. The time dependence of the writhe of a filament of length L is ([Wr(t) - Wr(0)]2) > approximately Lt(1/4). Simulations, on a simple model of a stiff polymer, are used to confirm scaling arguments.
openaire   +2 more sources