Results 131 to 140 of about 62,089 (297)

Stem cell mechanobiology

open access: yes, 2010
Stem cells are undifferentiated cells that are capable of proliferation, self-maintenance and differentiation towards specific cell phenotypes. These processes are controlled by a variety of cues including physicochemical factors associated with the ...
Jonathan J. Campbell   +7 more
core   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

Data and model driven dynamic stiffness testing method for rolling bearings and experimental study

open access: yes机车电传动
The dynamic stiffness of traction motor bearings directly affects the dynamic performance and operational stability of rail transit rotor systems.
LI Yeteng   +4 more
doaj  

Dynamic stiffness matrix for axially vibrating stochastic rods using Stratonovich's averaging principle

open access: yes, 1997
The problem of determining the dynamic stiffness matrix of a rod with broad band randomly varying mass and stiffness properties is considered. The governing stochastic boundary value problem is solved.
Manohar, CS
core  

Measurementand identification of dynamic translational stiffness matrix on machine tools understatic preloads [Elektronisk resurs]

open access: yes, 2021
Dynamic stiffness is an important characteristic of production machinery, as it contributes to its ability to maintain the position ofthe tool centre point accurately and precisely under loads.
Gonzalez, Monica,   +3 more
core  

Packed Hydrogel Microfibers as Scaffolds Supporting Dynamic Cellular Behavior and Biomaterial Inks in 3D Printing

open access: yesAdvanced Healthcare Materials, EarlyView.
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal   +7 more
wiley   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett   +7 more
wiley   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

open access: yesAdvanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima   +15 more
wiley   +1 more source

Dynamic behavior of Jeffcott rotors with an arbitrary slant crack orientation on the shaft

open access: yesApplied and Computational Mechanics, 2012
Dynamic behaviour of a Jeffcott rotor system with a slant crack under arbitrary crack orientations is investigated. Using concepts of fracture mechanics, flexibility matrix and stiffness matrix of the system are calculated. The system equations motion is
Ziaei-Rad S., Ghayour M., Ramezanpour R.
doaj  

Home - About - Disclaimer - Privacy