Results 161 to 170 of about 14,170,078 (259)

An ATP‐Driven N Protein–DDX21 Molecular Switch Dynamically Controls SARS‐CoV‐2 RNA G‐Quadruplex Heterogeneity

open access: yesAdvanced Science, EarlyView.
An ATP‐driven molecular switch, comprising viral nucleocapsid (N) protein and host helicase DDX21, dynamically modulates SARS‐CoV‐2 RNA G‐quadruplex (G4) heterogeneity. These viral G4s feature non‐canonical ion‐dependence and act as energy‐sensitive structural checkpoints.
Ya‐Ting Zheng   +8 more
wiley   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

COMPUTABLE GENERAL EQUILIBRIUM MODELS FOR THE CENTRAL AND EASTERN EUROPEAN EU MEMBER STATES: A SURVEY [PDF]

open access: yes
The accession of twelve Central and Eastern European countries (CEEC) to the European Union (in 2004 and 2007) has given rise to new challenges in evaluating the effects of integration, for both the old and the new member states. These issues can only be
Mohora, Maria C., Bayar, Ali
core  

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

Transport–Reaction–Signal Coupling in Lateral Flow Assays for Next‐Generation Point‐of‐Care Diagnostics

open access: yesAdvanced Science, EarlyView.
Lateral flow assays are evolving into interdisciplinary, system‐level sensing platforms. Recent innovations are deconstructed through coupled phases of mass transfer, reaction, and signal transduction, revealing interdependence across porous materials, interfacial chemistry, nanolabels, readout devices, and data‐enabled analysis.
Yan Pan   +6 more
wiley   +1 more source

Depth‐to‐Areal Staging Heterogeneity Preceding Lithium Plating in Graphite Anodes Revealed by Operando Imaging

open access: yesAdvanced Science, EarlyView.
Fast charging drives graphite anodes far from equilibrium, yet where lithium plating begins has remained hidden. Operando optical microscopy here reveals that neighboring regions advance through the staging sequence asynchronously, and that domains reaching advanced lithiation earliest become the preferential sites where plating initiates.
Tae Young Choi   +7 more
wiley   +1 more source

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