Results 191 to 200 of about 1,139 (243)

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

Portal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf, Mahboobeh Ebrahimi Varkiani, Saeid Abroun, Pedram Asadi‐Sarabi, Shukoofeh Torabi, Elham Rismani, Mohammad Majd Hammour, Andreas K. Nüssler, Massoud Vosough   +8 more
wiley   +1 more source

The how and why for multiple forms of hippocampal LTP. [PDF]

Front Synaptic Neurosci
Gall CM, Le AA, Lynch G.
europepmc   +1 more source

Synthesis of Poly(Itaconate)s With High Monomer Conversion Applying Emulsion Polymerization

Journal of Polymer Science, Volume 63, Issue 6, Page 1284-1296, 15 March 2025.
Itaconic acid and its derivatives are a promising and bio‐based substitute for oil‐based polymers such as acrylates. In this study, the optimization of polymerization of itaconic acid esters is described by applying emulsion polymerization leading to high reaction conversions and low residual monomer contents. ABSTRACT Itaconic acid and its derivatives
S. Charlotte Fischer von Mollard, Nico Ueberschaar, Martin Schreiber, Frank Kamphuis, Stefan Zechel, Martin D. Hager   +5 more
wiley   +1 more source

Quantifying the Surface Deformation of Pingos on the Alaskan North Slope Using Interferometric Synthetic Aperture Radar (InSAR)

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Pingos are large mounds with cores formed of intrusive ice that form in periglacial landscapes. These ice structures can form in regions of discontinuous permafrost, commonly as hydraulic or open‐system pingos, or in locations of continuous permafrost, commonly as hydrostatic or closed‐system pingos.
Venezia M. Follingstad, Roger J. Michaelides, Matthew R. Siegfried, Tyler M. Meng, John Bradford, Kynan H. G. Hughson, Alexia R. Kubas, Andrew Mullen, Enrica Quartini, Austin Routt, Hanna G. Sizemore, Andrei Swidinsky, Britney E. Schmidt   +12 more
wiley   +1 more source

Genomics and epigenomics of tissue repair: Implications for personalized medicine

Precision Medical Sciences, EarlyView.
Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi, Chandrashekar Thalluri, Sarad Pawar Naik Bukke, Piyali Dey, Mallikarjun Vasam, Ananda Kumar Chettupalli, Swetha Kumari Koduru, Gali Avinash Kumar   +7 more
wiley   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Roll‐to‐Roll Processing of Biodegradable Multilayer Barrier Packaging Structures

Packaging Technology and Science, EarlyView.
This work demonstrates that novel packaging materials built using biobased and biodegradable materials can be produced in pilot‐scale and converted into functional barrier packaging. The proposed structures are anticipated to make a strong impact in use‐cases where the risk of environmental littering is elevated, such as snacks and take away meals ...
Enni Luoma, Aayush Kumar Jaiswal, Vinay Kumar, Minna Vikman, Kirsi Kataja, Ali Harlin   +5 more
wiley   +1 more source

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Efficient VM Selection Heuristics for Dynamic VM Consolidation in Cloud Datacenters

2018 IEEE Intl Conf on Parallel & Distributed Processing with Applications, Ubiquitous Computing & Communications, Big Data & Cloud Computing, Social Computing & Networking, Sustainable Computing & Communications (ISPA/IUCC/BDCloud/SocialCom/SustainCom), 2018
Dynamic Consolidation of Virtual Machines (VMs) in a cloud data center requires live migration of VMs from over-utilized hosts. A primary but relatively an ignored part of consolidation process is the efficient selection of Virtual Machines from an over-utilized host for migration. Two VM selection policies, Threshold Based Selection (TBS) and Capacity
Hammad Qaiser, Gao Shu
openaire   +2 more sources

Evaluation of cluster K-Means as VM selection in dynamic VM consolidation

2016 22nd Asia-Pacific Conference on Communications (APCC), 2016
The paper focused on the evaluation of K-Means as VM Selection in Dynamic VM Consolidation. The research has compared the performance of several numbers of cluster K-Means in VM selection with another method such as Minimum Migration Time (MMT) and Random Choice (RC).
Guruh Fajar Shidik, Nani Sri Sulistyowati, Manggiardi B. W. Tirta   +2 more
openaire   +1 more source

An efficient energy-aware approach for dynamic VM consolidation on cloud platforms

Cluster Computing, 2021
The cloud computing environments rely heavily on virtualization that enables the physical hardware resources to be shared among cloud users by creating virtual machines (VMs). With an overloaded physical machine, the resource requests by virtual machines may not be fulfilled, which results in Service Level Agreement (SLA) violations. Moreover, the high
openaire   +2 more sources