The Clinical Pharmacogenetics Implementation Consortium (CPIC) TPMT/NUDT15 Pharmacogene Curation Expert Panel (PCEP) conducted a comprehensive review of clinical, laboratory, and computational evidence to determine the clinical function assignments for TPMT and NUDT15 star alleles.
Bailey M. Tibben +10 more
wiley +1 more source
A novel approach to reliable and flexible distributed computing with virtualization in smart healthcare applications. [PDF]
Dhiman G +4 more
europepmc +1 more source
A Dynamic Business Modeling Approach to Port Sustainability: The Western Sicily Port Authority Case
ABSTRACT Ports are critical nodes in global trade and economic development, yet they generate substantial environmental and social externalities—including greenhouse gas emissions, air, noise, and water pollution, and adverse impacts on host communities—that demand integrated and forward‐looking governance.
Martina Vivoli +3 more
wiley +1 more source
Dynamic multi objective task scheduling in cloud computing using reinforcement learning for energy and cost optimization. [PDF]
Yu X, Mi J, Tang L, Long L, Qin X.
europepmc +1 more source
This work integrates 5 years of field data from the Aquistore CCS project with a non‐isothermal THM modeling framework to explain how cold CO2 injection alters injectivity over time. The study shows that sustained cooling near the wellbore reduces effective stresses, promotes tensile micro‑cracking, and leads to semi‑reversible permeability enhancement
Alireza Rangriz Shokri +3 more
wiley +1 more source
AI-powered VM selection: Amplifying cloud performance with dragonfly algorithm. [PDF]
Rashmi S +7 more
europepmc +1 more source
A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble +2 more
wiley +1 more source
Implication of the thalamus in sleep alterations observed in Alzheimer's disease. [PDF]
Burnet-Merlin C, Hay YA, Brécier A.
europepmc +1 more source
Water Electrolysis Technologies for Extraterrestrial Water Resource Conversion
This paper reviews four water electrolysis technologies for extraterrestrial water conversion: alkaline water electrolysis, proton exchange membrane water electrolysis, solid oxide water electrolysis, and anion exchange membrane water electrolysis. It elaborates on their mechanisms, components, and integration, highlighting challenges such as water ...
Yawen Jiang +6 more
wiley +1 more source
Neuromechanical characteristics of breaststroke in adolescent swimmers across different performance levels: a comparative analysis. [PDF]
Liu G, Zhu H, Ma J, Zhu H, He Z.
europepmc +1 more source

