Results 141 to 150 of about 46,048,977 (302)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Sensitivity for Set-Valued Discrete Dynamical Systems [PDF]

, 2016
Any discrete topological dynamical system can be extended to some hyper- space dynamical system. So the natural question to know if a property of the base system transfers on the extended one, and viceversa, arises.
MIRANDA, Annamaria
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A generalized wave action conservative equation for the dissipative dynamical system in the nearshore region

, 2003
To describe the various complex mechanisms of the dissipative dynamical system between waves, currents, and bottoms in the nearshore region that induce typically the wave motion on large-scale variation of ambient currents, a generalized wave action ...
Huang H
core   +2 more sources

Unsupervised learning of stationary and switching dynamical system models from Poisson observations. [PDF]

J Neural Eng, 2023
Song CY, Shanechi MM.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

On fast simulation of dynamical system with neural vector enhanced numerical solver. [PDF]

Sci Rep, 2023
Huang Z, Liang S, Zhang H, Yang H, Lin L.   +4 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Preliminary evidence for chaotic signatures in host-microbe interactions

mSystems
Host-microbe interactions constitute dynamical systems that can be represented by mathematical formulations that determine their dynamic nature and are categorized as deterministic, stochastic, or chaotic.
Yehonatan Sella, Nichole A. Broderick, Kaitlin M. Stouffer, Deborah L. McEwan, Frederick M. Ausubel, Arturo Casadevall, Aviv Bergman   +6 more
doaj   +1 more source

Time Rescaling of a Primal-Dual Dynamical System with Asymptotically Vanishing Damping. [PDF]

Appl Math Optim, 2023
Hulett DA, Nguyen DK.
europepmc   +1 more source