Results 141 to 150 of about 170,832 (317)

Breaking reflection symmetry: evolving long dynamical cycles in Boolean systems

New Journal of Physics
In interacting dynamical systems, specific local interaction rules for system components give rise to diverse and complex global dynamics. Long dynamical cycles are a key feature of many natural interacting systems, especially in biology.
Mathieu Ouellet, Jason Z Kim, Harmange Guillaume, Sydney M Shaffer, Lee C Bassett, Dani S Bassett   +5 more
doaj   +1 more source

Backward bifurcation on HIV/AIDS SEI1I2TAR model with multiple interactions between sub-populations

Arab Journal of Basic and Applied Sciences
The HIV/AIDS model was dynamically analyzed in this study. The model has seven compartments: the uneducated, the educated, the HIV-positive who take antiretroviral therapy (ART), the HIV-positive who do not take ART, people receiving ART treatment ...
Ummu Habibah, Trisilowati, Tiara Rizki Tania, Labib Umam Al-Faruq   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reducibility by Moments of Linear Impulse Markov Dynamical Systems with Almost Constant Coefficients [PDF]

This paper deals with linear impulse dynamical systems on R^d whose parameters depend on an ergodic piece-wise constant Markov process with values from some phase space Y and on a small parameter ε.
Šadurskis, Kārlis, Pola, Aija, Carkovs, Jevgeņijs   +2 more
core  

The existence of traveling wave solutions for a bistable three-component lattice dynamical system [PDF]

, 2016
We study the traveling wave solutions for a three-component lattice dynamical system. This problem arises in the modeling of three species competing two food resources in an environment with migration in which the habitat is one-dimensional and is ...
Guo, Jong-Shenq;Wu, Chin-Chin
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source