Results 221 to 230 of about 170,832 (317)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

The fractional soliton solutions of the dynamical system of equations for ion sound and Langmuir waves: a comparative analysis. [PDF]

Sci Rep
Faridi WA, Jhangeer A, Riaz MB, Asjad MI, Muhammad T.   +4 more
europepmc   +1 more source

Coexistence of chaotic attractor and unstable limit cycles in a 3D dynamical system. [PDF]

Open Res Eur, 2021
Constantinescu D, Tigan G, Zhang X.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Relationship Between Intensive Passive Data Signals and Patterns of Binge-Eating Behaviors: From a Dynamical-System Approach. [PDF]

Clin Psychol Sci
Shi Q, Thornton LM, Kilshaw R, Flatt RE, Butner JE, Adamo C, Deboeck PR, Baucom BRW, Tregarthen J, Argue S, Bulik CM.   +10 more
europepmc   +1 more source

Turing instability in an economic-demographic dynamical system may lead to pattern formation on a geographical scale. [PDF]

J R Soc Interface, 2021
Zincenko A, Petrovskii S, Volpert V, Banerjee M.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Adaptive fixed-time TSM for uncertain nonlinear dynamical system under unknown disturbance. [PDF]

PLoS One
Ahmed S, Azar AT, Wang H.
europepmc   +1 more source

Single Neuronal Dynamical System in Self-Feedbacked Hopfield Networks and Its Application in Image Encryption. [PDF]

Entropy (Basel), 2021
Xu X, Chen S.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source