Results 191 to 200 of about 27,598 (253)

Self-Oscillatory Neuron-like Devices for Unconventional Computing Applications. [PDF]

Chem Rev
Rivera-Sierra G, Bisquert J, Fenollosa R.   +2 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Nonlinear dynamics of Nosema ceranae and the fragile resilience of honeybee colonies under environmental strain. [PDF]

Sci Rep
Salman AM, Mohd MH, Almansoori AKK, Manmi KMA.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Emergence of multifrequency activity in a laminar neural mass model. [PDF]

PLoS Comput Biol
de Palma Aristides R, Clusella P, Sanchez-Todo R, Ruffini G, Garcia-Ojalvo J.   +4 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Learning under uncertainty-Conservation of populations and persistence of dynamic resources through adaptive switching feedback controllers. [PDF]

PLoS One
Smith P, Guiver C.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A theory for self-sustained balanced states in absence of strong external currents. [PDF]

PLoS Comput Biol
Angulo-Garcia D, Torcini A.
europepmc   +1 more source

Quantitative Biology: Dynamics of living systems

Frontiers in Physiology, 2016
Noriko eHiroi, Viji M Draviam, Akira eFunahashi   +2 more
openaire   +1 more source