Results 211 to 220 of about 27,598 (253)

The integrated information Φ of an integrate and fire network. [PDF]

open access: yesPLoS Comput Biol
Danilczuk M, Pokropski M, Suffczynski P.
europepmc   +1 more source
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A Dynamical-Systems View of Stem Cell Biology

Science, 2012
During development, cells undergo a unidirectional course of differentiation that progressively decreases the number of cell types they can potentially become. Stem cells, however, keep their potential to both proliferate and differentiate. A very important issue then is to understand the characteristics that distinguish stem cells from other cell ...
Kunihiko Kaneko, Chikara Furusawa
exaly   +3 more sources

Applications of Dynamical Systems in Biology and Medicine

The IMA Volumes in Mathematics and Its Applications, 2015
This volume highlights problems from a range of biological and medical applications that can be interpreted as questions about system behavior or control. Topics include drug resistance in cancer and malaria, biological fluid dynamics, auto-regulation in the kidney, anti-coagulation therapy, evolutionary diversification and photo-transduction ...
exaly   +2 more sources

Scaling for Dynamical Systems in Biology

Bulletin of Mathematical Biology, 2017
Asymptotic methods can greatly simplify the analysis of all but the simplest mathematical models and should therefore be commonplace in such biological areas as ecology and epidemiology. One essential difficulty that limits their use is that they can only be applied to a suitably scaled dimensionless version of the original dimensional model.
openaire   +2 more sources

Feedback dynamics and cell function: Why systems biology is called Systems Biology

Molecular BioSystems, 2005
Abstract A new paradigm, like Systems Biology, should challenge the way research has been conducted previously. This Opinion article aims to present Systems Biology, not as the application of engineering principles to biology but as a merger of systems- and control theory with molecular- and cell biology.
Olaf, Wolkenhauer, Mihajlo, Mesarovic
openaire   +2 more sources

Systems Biology Modeling of Cancer Nonlinear Dynamics

2023
Not unlike the climate or what holds the galaxies and planetary motions together, cancer biology has an intrinsic nonlinear dynamic. In this overview we will outline how to connect temporal measurements of a nonlinear dynamical and unstable complex system, such as cancer, with well-established engineering methods, old and new, that are applied in ...
openaire   +3 more sources

Dynamics of biological systems: role of systems biology in medical research

Expert Review of Molecular Diagnostics, 2006
Cellular systems are networks of interacting components that change with time in response to external and internal events. Studying the dynamic behavior of these networks is the basis for an understanding of cellular functions and disease mechanisms.
Assmus, HE Assmus, Heike E.   +3 more
openaire   +4 more sources

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