Results 231 to 240 of about 139,067 (282)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Robust coexistence in competitive ecological communities. [PDF]

Nat Commun
Lechón-Alonso P, Kundu S, Lemos-Costa P, Capitán JA, Allesina S.   +4 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Author Correction: Neural mechanisms balancing accuracy and flexibility in working memory and decision tasks. [PDF]

NPJ Syst Biol Appl
Yan H, Wang J.
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Emergent multiscale dynamics in photonic neurons with dual feedback. [PDF]

Sci Rep
Aragoneses A.
europepmc   +1 more source

Aligning statistical models with inference goals in the neuroscience of language: A dual-dependency taxonomy. [PDF]

Imaging Neurosci (Camb)
Bouton S, Chambon V, Golestani N, Formisano E, Proix T, Giraud AL.   +5 more
europepmc   +1 more source

Data-driven identification of biological systems using multi-scale analysis. [PDF]

PLoS Comput Biol
Muhammed I, Manias DM, Goussis DA, Hatzikirou H.   +3 more
europepmc   +1 more source

Mining higher-order triadic interactions. [PDF]

Nat Commun
Niedostatek M, Baptista A, Yamamoto J, Kurths J, Sanchez Garcia R, MacArthur BD, Bianconi G.   +6 more
europepmc   +1 more source

Changing cognitive chimera states in human brain networks with age: Variations in cognitive integration and segregation. [PDF]

PLoS Comput Biol
Patton A, Davidsen J.
europepmc   +1 more source