Results 241 to 250 of about 139,067 (282)

Let there be multifunctionality: Uncovering the criticality zoo of the AC-DC genetic circuit

Maretvadakethope S, Aor I, Fischer MM, Pedrosa ÀP, Schaerli Y, Perez-Carrasco R.   +5 more
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Scaling for Dynamical Systems in Biology

Bulletin of Mathematical Biology, 2017
Asymptotic methods can greatly simplify the analysis of all but the simplest mathematical models and should therefore be commonplace in such biological areas as ecology and epidemiology. One essential difficulty that limits their use is that they can only be applied to a suitably scaled dimensionless version of the original dimensional model.
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Nonhomogeneous Dynamic Bayesian Networks in Systems Biology

2011
Dynamic Bayesian networks (DBNs) have received increasing attention from the computational biology community as models of gene regulatory networks. However, conventional DBNs are based on the homogeneous Markov assumption and cannot deal with inhomogeneity and nonstationarity in temporal processes.
Sophie, Lèbre, Frank, Dondelinger, Dirk, Husmeier   +2 more
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Good practices for building dynamical models in systems biology

Science Signaling, 2015
Spherical cows may result if dynamic modeling of signaling is not done correctly.
Evren U, Azeloglu, Ravi, Iyengar
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Dynamics of biological systems: role of systems biology in medical research

Expert Review of Molecular Diagnostics, 2006
Cellular systems are networks of interacting components that change with time in response to external and internal events. Studying the dynamic behavior of these networks is the basis for an understanding of cellular functions and disease mechanisms.
Assmus, HE Assmus, Heike E., Herwig, R Herwig, Rolf, Cho, KH Cho, Kwang-Hyun, Wolkenhauer, O Wolkenhauer, Olaf   +3 more
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Dynamical Systems in Biology: A Short Introduction

2019
The contributions to this textbook are based on a summer school on Dynamics of Biological Systems as part of the series “Seminaire de Mathematiques Superieures,” which was held at the University of Alberta in June 2016. The lectures cover a wide variety of topics and it would be presumptuous to assume that all readers are equally familiar with all the ...
Thomas Hillen, Mark A. Lewis
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Discrete Dynamical Systems: With Applications in Biology -2nd Edition

2021
Discrete-time dynamical systems or difference equations have been increasingly used to model the biological and ecological systems for which there is time interval between each measurement. This modeling approach is done through using the iterative maps.
Azizi, Tahmineh, Alali, Bacim, Kerr, Gabriel   +2 more
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High-Confidence Predictions in Systems Biology Dynamic Models

2014
No
Villaverde, A. F., Bongard, Sophia, Mauch, Klaus, Müller, Dirk, Balsa-Canto, Eva, Schmid, Joachim, Banga, Julio R.   +6 more
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Modeling systems-level dynamics: Understanding without mechanistic explanation in integrative systems biology

Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 2015
In this paper we draw upon rich ethnographic data of two systems biology labs to explore the roles of explanation and understanding in large-scale systems modeling. We illustrate practices that depart from the goal of dynamic mechanistic explanation for the sake of more limited modeling goals.
Miles, MacLeod, Nancy J, Nersessian
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