Results 111 to 120 of about 3,971,309 (348)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Newtonian dynamical systems admitting normal blow-up of points [PDF]

open access: yesarXiv, 2000
Class of Newtonian dynamical systems admitting normal blow-up of points in Riemannian manifolds is considered. Geometric interpretation for weak normality condition, which arose earlier in the theory of dynamical systems admitting the normal shift of hypersurfaces, is found.
arxiv  

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Performance analysis of control allocation using data‐driven integral quadratic constraints

open access: yesAdvanced Control for Applications, Volume 4, Issue 4, December 2022., 2022
Abstract A new method is presented for evaluating the performance of a nonlinear control allocation system within a linear control loop. To that end, a worst‐case gain analysis problem is formulated that can be readily solved by means of well‐established methods from robustness analysis using integral quadratic constraints (IQCs).
Manuel Pusch   +2 more
wiley   +1 more source

Interpretable predictions of chaotic dynamical systems using dynamical system deep learning

open access: yesScientific Reports
Making accurate predictions of chaotic dynamical systems is an essential but challenging task with many practical applications in various disciplines.
Mingyu Wang, Jianping Li
doaj   +1 more source

Dynamic Equations, Control Problems on Time Scales, and Chaotic Systems

open access: yesChaos Theory and Applications, 2023
The unification of integral and differential calculus with the calculus of finite differences has been rendered possible by providing a formal structure to study hybrid discrete-continuous dynamical systems besides offering applications in diverse fields
Martin Bohner
doaj  

Understanding and Predicting Nonlinear Turbulent Dynamical Systems with Information Theory

open access: yesAtmosphere, 2019
Complex nonlinear turbulent dynamical systems are ubiquitous in many areas. Quantifying the model error and model uncertainty plays an important role in understanding and predicting complex dynamical systems.
Nan Chen, Xiao Hou, Qin Li, Yingda Li
doaj   +1 more source

A note on arithmetic topology and dynamical systems [PDF]

open access: yesarXiv, 2002
We discuss analogies between the etale site of arithmetic schemes and the algebraic topology of dynamical systems. The emphasis is on Lefschetz numbers. We also discuss similarities between infinite primes in arithmetic and fixed points of dynamical systems.
arxiv  

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

open access: yesFEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo   +2 more
wiley   +1 more source

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