Results 151 to 160 of about 3,971,309 (348)

Impact of enhanced leaf model on dose calculation accuracy in single‐isocenter multitarget stereotactic radiosurgery treatments

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Single‐isocenter multitarget (SIMT) radiosurgery has become increasingly popular as advancement in planning and delivery systems have made this approach clinically viable. With targets varying in size and distance from isocenter, SIMT plans are highly complex with dynamic multileaf collimator (MLC) motion.
Hem Moktan   +3 more
wiley   +1 more source

Computational Dynamical Systems [PDF]

open access: yesarXiv
We study the computational complexity theory of smooth, finite-dimensional dynamical systems. Building off of previous work, we give definitions for what it means for a smooth dynamical system to simulate a Turing machine. We then show that 'chaotic' dynamical systems (more precisely, Axiom A systems) and 'integrable' dynamical systems (more generally,
arxiv  

Epigenome‐wide association study, meta‐analysis, and multiscore profiling of whole blood in Parkinson's disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie   +4 more
wiley   +1 more source

Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez   +15 more
wiley   +1 more source

Liraglutide for idiopathic intracranial hypertension: a real‐world propensity score‐matched study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Idiopathic intracranial hypertension (IIH) is a neurological disorder predominantly affecting young women with obesity, characterized by elevated intracranial pressure. While current treatments include weight loss counseling, medical therapies, and surgical interventions, their limitations necessitate exploring novel therapeutic ...
Ahmed Y. Azzam   +13 more
wiley   +1 more source

Koopman Operators for Global Analysis of Hybrid Limit-Cycling Systems: Construction and Spectral Properties [PDF]

open access: yesarXiv
This paper reports a theory of Koopman operators for a class of hybrid dynamical systems with globally asymptotically stable periodic orbits, called hybrid limit-cycling systems. We leverage smooth structures intrinsic to the hybrid dynamical systems, thereby extending the existing theory of Koopman operators for smooth dynamical systems.
arxiv  

An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
By applying the tensor model, we analysed lesion orientation and the directionality of lesion expansion/contraction in multiple sclerosis. Each lesion is summarized as an ellipsoid, and the tensor model is applied to calculate lesion anisotropy. From the top to the bottom white matter atlas, surface‐in gradient segmentation and venous atlas used in the
Ermelinda De Meo   +9 more
wiley   +1 more source

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