Results 181 to 190 of about 168,786,670 (266)

A network dynamical simulation model for the study of antibiotic resistance in microbial communities. [PDF]

Gut Microbes
Silva-Magaña MA, Mora-Flores LP, Pita-Galeana MA, Hernández-Lemus E, de Anda-Jáuregui G.   +4 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Privacy-preserving and robust mouse dynamics authentication using hybrid transformer-CNN and federated learning. [PDF]

Front Artif Intell
Sasikumar K, Nagarajan S.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Climate change, rodent ecology, and the rising risk of hantavirus outbreaks: an alarming public health concern. [PDF]

Front Microbiol
Shrivastava SR, Bobhate PS, Mendhe H, Bankar N, Tidake A, Petkar P.   +5 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Dissecting Fluctuating Selection: A Unified Population and Quantitative Genetics Framework. [PDF]

Genome Biol Evol
Tuyishimire E, Burke MK, King EG.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

How the brain dances across critical boundaries. [PDF]

PLoS Biol
Sederberg AJ.
europepmc   +1 more source

Latent growth models matched to research questions to answer questions about dynamics of change in multiple processes. [PDF]

J Clin Epidemiol, 2017
Muniz-Terrera G, Robitaille A, Kelly A, Johansson B, Hofer S, Piccinin A.   +5 more
europepmc   +1 more source