Results 51 to 60 of about 42,989 (261)

Ensuring psychological health of the participants in the educational process in the crisis wartime conditions

open access: yesУніверситети і лідерство
The study raises the issue of ensuring psychological health of participants in the educational process of higher education institutions (HEIs) who carry out educational activities in crisis conditions caused by the military events in Ukraine in 2014 and ...
Tetiana Sych
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Dynamics of School Culture and Leadership in Educational Institutions

open access: yesNPRC Journal of Multidisciplinary Research
School culture and leadership are vital for student success. This study explores the dynamic interplay between School culture and leadership in educational institutions, emphasizing their collective impact on student achievement and well-being. Drawing on a comprehensive review of literature, the paper examines how effective leadership practices ...
Yashodhara Pant, Rabindra Shiwakoti
openaire   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Strategi Pemasaran Jasa Pendidikan dalam Meningkatkan Nilai Jual Madrasah

open access: yesMadaniyah: Terciptanya Insan Akademis Berkualitas & Berakhlak Mulia, 2017
Competition in education becomes inevitable, many educational institutions are abandoned by customers so that the negative dynamics of some educational institutions. Meanwhile, Islamic educational institutions, especially madrassas, are still overwhelmed
Imam Faizin
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

MOOCs, institutional policy and change dynamics in higher education [PDF]

open access: yesHigher Education, 2014
The last couple of years have witnessed a growing debate about online learning in higher education, notably in response to the global massive open online course (MOOC) phenomenon. This paper explores these developments from an institutional policy perspective, drawing on an analysis of the initial stages of different approaches to MOOCs and e-learning ...
openaire   +2 more sources

The Design of Educational Programs in System Dynamics at Worcester Polytechnic Institute (WPI) [PDF]

open access: yesSystems, 2014
Educational programs leading to degrees in system dynamics are rare and thus of critical importance to the future of the field of system dynamics. However, to a large extent such programs have not yet been made transparent to the system dynamics community as a whole.
Oleg V. Pavlov   +4 more
openaire   +3 more sources

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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